Tabla de Contenidos:
  • Intro
  • The Human Hypothalamus: Middle and Posterior Region
  • Copyright
  • Handbook of Clinical Neurology 3rd Series
  • Foreword
  • Preface
  • The HCN volumes on the Human Hypothalamus
  • The hypothalamus: Arbitrary borders
  • References
  • Contributors
  • Contents
  • Contents of related volumes
  • Chapter 1: Introduction: The middle and posterior hypothalamus
  • Section 6#: Supraoptic and Paraventricular Nucleus: More than a Neuroendocrine System
  • Section 7: Zona Incerta
  • Section 8: Ventromedial Nucleus and Dorsomedial Nucleus
  • Section 9: Circumventricular Organs of the Hypothalamus
  • Section 10: Lateral Tuberal Nucleus
  • Section 11: Lateral Hypothalamic Area, Perifornical Area
  • Section 12: Tuberomamillary Complex
  • Section 13: Subthalamic Nucleus
  • Section 14: Corpora Mamillaria, Fornix, and Mamillothalamic Tract
  • References
  • Section 6: Supraoptic and paraventricular nucleus more than a neuroendocrine system
  • Chapter 2: Vasopressin and oxytocin beyond the pituitary in the human brain
  • Accessory Magnocellular Neuroendocrine System of the Hypothalamus
  • Vasopressin- and Oxytocin-Containing Neurons and Fibers in the Forebrain
  • Vasopressin and Oxytocin Are Involved in Motivated Social Behavior
  • Localization of the Neurons Involved in Behavioral and Physiological Functions and Targeted by Vasopressinergic and Oxytociner
  • Forebrain
  • Brainstem and spinal cord
  • Vasopressin in the Suprachiasmatic Nucleus
  • Vasotocin, Vasopressin, and Oxytocin in the Mammalian Pineal Gland
  • Conclusions
  • References
  • Chapter 3: Central and peripheral release of oxytocin: Relevance of neuroendocrine and neurotransmitter actions for physi ...
  • Introduction
  • Organization of the Hypothalamic-Neurohypophyseal (HHNS) System
  • Parvocellular Oxytocin Neurons of the Hypothalamus: Master Cells Arranging the HHNS Activity?.
  • Heterogeneity of Oxytocin Neurons
  • Synaptic vs Nonsynaptic Oxytocin Release
  • Intracellular Oxytocin Receptor Signaling
  • Oxytocin System in Monkeys and Human
  • Oxytocin in Human Health
  • Perspectives
  • Acknowledgments
  • References
  • Chapter 4: Organization of the neuroendocrine and autonomic hypothalamic paraventricular nucleus
  • Introduction1
  • Hypothalamic Integration of Time of Day
  • Control of the Daily Rhythm in HPA axis Activity
  • Control of the Daily Rhythm in HPT Axis Activity
  • Control of the Daily Rhythm in Prolactin Release
  • Control of the Daily Rhythm in Pineal Melatonin Release
  • Control of the Daily Rhythm in Plasma Glucose Concentrations
  • Control of the Daily Rhythm in Feeding-Induced Insulin Responses
  • Multiple Subpopulations of Preautonomic Neurons
  • Future Perspective
  • References
  • Chapter 5: Sex differences of oxytocin and vasopressin in social behaviors
  • Introduction
  • Models and Interventions
  • Sexually Dimorphic Influences of OT on Social Cognition
  • Partner preference and sexual orientation
  • Memory modulation
  • Emotion regulation
  • Trust-related behaviors
  • Sexually Dimorphic Influences of VP on Social Cognition
  • Effects of OT and VP on Social Cognition of Women During Pregnancy, Birth, and Lactation
  • OT in peripartum period
  • VP in peripartum period
  • Discussion
  • References
  • Chapter 6: Oxytocin, eating behavior, and metabolism in humans
  • Oxytocin Neurophysiology-Relation to Energy Homeostasis
  • Endogenous Oxytocin Levels, Eating Behavior, and Metabolic Status in Humans
  • Measurement of oxytocin
  • Endogenous oxytocin levels in healthy individuals and patients with disrupted oxytocin pathways
  • Oxytocin levels in obesity and metabolic disorders
  • The Effects of Oxytocin Administration on Caloric Intake and Metabolism.
  • The Effects of Oxytocin Administration in Individuals with Obesity and Suspected Insult to Oxytocin Pathways
  • Therapeutic Opportunities and Challenges
  • Competing interests statement
  • References
  • Chapter 7: The supraoptic and paraventricular nuclei in healthy aging and neurodegeneration
  • The Supraoptic and Paraventricular Nuclei in Healthy Aging
  • Morphological changes in aging
  • Sex differences in aging
  • Vasopressin
  • Oxytocin
  • Corticotropin-releasing hormone
  • Thyrotropin-releasing hormone
  • Hormone changes in aging
  • Vasopressin
  • Oxytocin
  • Corticotropin-releasing hormone
  • Thyrotropin-releasing hormone
  • Circuit changes in aging
  • Hypothalamic-pituitary-adrenal axis
  • Hypothalamic-pituitary-thyroid axis
  • The Supraoptic and Paraventricular Nuclei in Neurodegeneration
  • Alzheimer's disease
  • Abnormal inclusions and aggregates
  • Neuronal loss and other pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Frontotemporal dementia
  • Abnormal inclusions and aggregates
  • Neuronal loss and other pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Amyotrophic lateral sclerosis
  • Abnormal inclusions and aggregates
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Progressive supranuclear palsy
  • Abnormal inclusions and aggregates
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Parkinson's disease
  • Abnormal inclusions and aggregates
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Dementia with Lewy bodies
  • Abnormal inclusions and aggregates
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Multiple system atrophy
  • Abnormal inclusions and aggregates.
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Huntington's disease
  • Abnormal inclusions and aggregates
  • Neuronal loss and pathological changes
  • Hormonal changes
  • Circuit alterations and disruption
  • Conclusion
  • References
  • Chapter 8: Perinatal stress and epigenetics
  • Introduction: DNA Methylation and Cellular Identity
  • DNA Methylation and Gene Function
  • Epigenetic Programming of the HPA Axis by Maternal Behavior and Its Reversal by Epigenetic Regulators
  • Early Life Stress-Mediated Epigenetic Reprogramming of the HPA axis: Epigenetic Changes in the Hypothalamus
  • Early Life Stress/Adversity Causes Broad Epigenetic Changes Across the Genome Which Are Evolutionary Conserved
  • The Effect of Early Life Stress/Adversity-related Broad Epigenetic Changes in Peripheral Tissues Outside the
  • Socioeconomic Positioning and Epigenetic Programming
  • Early Life Stress and PTSD
  • Cross-Generational Effects of Trauma
  • Early Life Stress Methylation and Metabolic Control
  • Epigenetic Processes Mediating Effects of Stress During Adulthood
  • DNA Methylation Programming of the HPA axis in Response to ELS: A Genomic Mechanism of Adaptation
  • Dynamic Epigenetic Programming in Response to Early Life Experience: Setting up Future Gene Expression Trajectories
  • What Are the Mechanisms that Mediate Between Experience and DNA Methylation Alterations in the HPA axis and Somatic Tissues an
  • Summary and Perspective
  • Acknowledgment
  • References
  • Chapter 9: The hypothalamus in anxiety disorders
  • Introduction
  • Oxytocin
  • Corticotropin-Releasing Hormone
  • Thyrotropin-Releasing Hormone
  • Conclusion
  • Acknowledgment
  • References
  • Chapter 10: Congenital isolated central hypothyroidism: Novel mutations and their functional implications
  • Introduction.