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|d OCLCO
|d EBLCP
|d OCLCQ
|d OCLCO
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|z 9780128169834
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|z 0128169834
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|a (OCoLC)1242943284
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|a QR182.2.M36
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|a 616.079015118
|2 23
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|a Chen, Bor-Sen,
|e author.
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|a Systems immunology and infection microbiology /
|c Bor-Sen Chen.
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|a Amsterdam :
|b Academic Press,
|c 2021.
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| 300 |
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|a 1 online resource (1 volume) :
|b illustrations (colour)
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a Print version record.
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|a Front Cover -- Systems Immunology and Infection Microbiology -- Copyright Page -- Contents -- Preface -- 1 Introduction to systems immunology and infection microbiology -- 1.1 Introduction -- 1.2 Content and general outline of the book -- I. Systems Immunology -- 2 Biological network modeling and system identification in systems immunology and infection microbiology -- 2.1 System identification for gene regulatory network -- 2.1.1 Least square parameter estimation method -- 2.1.2 Maximum likelihood parameter estimation method -- 2.2 System identification of protein-protein interaction network
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|a 2.3 System identification of integrated genetic and epigenetic network via high throughput next generation sequencing data -- 2.4 Conclusion -- 3 Identifying the gene regulatory network of systems inflammation in humans by system dynamic model via microarray data and ... -- 3.1 Introduction -- 3.2 Construction of candidate inflammatory gene regulatory network in response to inflammatory stimulus -- 3.3 Pruning the candidate gene regulatory network via a dynamic gene regulatory model -- 3.4 On the construction of inflammatory gene regulatory network in immune system
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|a 3.5 Biological insight and discussion -- 3.6 Conclusion -- 3.7 Material and methods -- 3.7.1 Dataset selection -- 3.7.2 Construction of candidate gene networks of systematic inflammation -- 3.7.3 Constructing a dynamic regulatory model for gene regulatory network via microarray data -- 3.7.4 Pruning the candidate gene regulatory network -- 3.8 Appendix -- 3.8.1 Dataset selection -- 3.8.2 Gene network construction -- 3.8.3 Discussion -- 4 Dynamic cross-talk analysis among signaling transduction pathways in the vascular endothelial inflammatory response syste ... -- 4.1 Introduction
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|a 4.3.3 Investigation of the interleukin-1 receptor and Toll-like receptor 4 signaling pathways -- 4.3.4 Cross-talk analysis of the protein-protein interaction networks -- 4.4 Discussion -- 4.4.1 Dynamic progression of the protein-protein interaction networks -- 4.4.2 Specific architecture in the signaling transduction network -- 4.4.3 Possible existence of Toll-like receptor 4 endogenous ligand -- 4.4.4 Negative feedback controls of the cross talks among multiple signaling pathways -- 4.5 Conclusion -- 4.6 Appendix: Supplementary methods
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| 650 |
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|a Immune system
|x Mathematical models.
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| 650 |
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|a Infection
|x Mathematical models.
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| 650 |
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6 |
|a Syst�eme immunitaire
|0 (CaQQLa)201-0005078
|x Mod�eles math�ematiques.
|0 (CaQQLa)201-0379082
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| 650 |
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6 |
|a Infection
|0 (CaQQLa)201-0013311
|x Mod�eles math�ematiques.
|0 (CaQQLa)201-0379082
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| 650 |
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7 |
|a Infection
|x Mathematical models
|2 fast
|0 (OCoLC)fst00972333
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| 776 |
0 |
8 |
|i Print version:
|a Chen, Bor-Sen.
|t Systems immunology and infection microbiology.
|d Amsterdam : Academic Press, 2021
|z 9780128169834
|w (OCoLC)1233316352
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| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128169834
|z Texto completo
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