Cargando…

Microbial metabolism and disease /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Paley, Elena L. (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, [2021]
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Microbial Metabolism and Disease
  • Microbial Metabolism and Disease
  • Copyright
  • Contents
  • 1
  • Naturally occurring affectors of tRNA aminoacylation in transition from health to disease: interference in the ...
  • 1.1 Introduction
  • 1.2 Experimental evidences supporting the concept
  • 1.2.1 Tryptamine-induced neurodegeneration in cell and animal models
  • 1.2.2 Alzheimer disease is a systemic widespread disease
  • 1.2.3 Seizures and myoclonus in Alzheimer disease and in tryptamine-treated animals
  • 1.2.4 Serotonin (5-HT) or tryptamine syndrome
  • 1.2.5 Metabolic syndrome
  • 1.2.6 Tryptamine, biogenic amines, and polyamines affect tRNA aminoacylation and protein biosynthesis
  • 1.2.7 Protein biosynthesis in Alzheimer disease and in cancer
  • 1.2.8 Mutations of genes encoding cytoplasmic (WARS) and mitochondrial (WARS2) TrpRS leading to TrpRS deficiency, Parkinsonism, a ...
  • 1.2.9 The accumulation of defective proteins induces antigenicity
  • 1.3 Conclusions
  • 2
  • Physicochemical, biochemical, and cell biology properties and byproducts of tryptamine and other "trace" amines
  • 3
  • Tryptophan metabolites and biogenic amines in physical exercises and metabolic syndrome
  • 4
  • Tryptamine in inflammation and regulation of gene transcription
  • 5
  • Genes encoding mammalian, plant, and microbial aromatic amino acid decarboxylase
  • 5.1 Mammalian aromatic acid decarboxylase
  • 5.2 Bacterial aromatic l-amino acid decarboxylases
  • 5.3 Fungal pyridoxal-dependent aromatic-l-amino-acid decarboxylase
  • 5.4 Plant tryptophan decarboxylase
  • 5.5 Conclusion
  • 6
  • Decarboxylases producing tryptamine and other biogenic amines in the human microbiome
  • 6.1 Conclusion
  • 7
  • Microbial shikimate pathway in diseases
  • 7.1 Apicomplexan parasites
  • 7.2 Effect of tryptamine and other tryptophan-related compounds on shikimate pathway enzymes
  • 7.3 Pyridoxal phosphate-dependent enzymes
  • 7.4 Metabolic engineering
  • 7.5 Inhibitors of shikimate pathway enzymes
  • 7.6 Conclusion
  • 8
  • Biogenic amines in fasting, feeding, and stress conditions
  • 8.1 Fasting, starvation, and feeding
  • 8.2 Anorectic effect
  • 8.3 Stress factors
  • 8.4 Stress and mucus
  • 8.5 Irritable bowel syndrome: poor sleep
  • 8.6 Conclusions
  • 9
  • Metabolites of shikimate and tryptophan pathways in coronavirus disease (COVID-19)
  • 9.1 Comparison of statistics for age-related diseases COVID-19 and Alzheimer disease
  • 9.2 Proteomic and metabolomic profiling of sera from COVID-19 patients and further discussion
  • 9.3 Postmortem studies of COVID-19 patients in different countries
  • 9.4 Conclusions
  • 10
  • Virulence factors
  • 10.1 Bacteria and virus interactions in influenza
  • 10.2 Decarboxylase and viral infection