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Genome editing : a practical guide to research and clinical applications /
"Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome edit...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2021.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 020 | |a 9780128236475 |q (electronic bk.) | ||
| 020 | |a 0128236477 |q (electronic bk.) | ||
| 020 | |z 9780128234846 | ||
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| 100 | 1 | |a Musunuru, Kiran, |e author. | |
| 245 | 1 | 0 | |a Genome editing : |b a practical guide to research and clinical applications / |c Kiran Musunuru. |
| 264 | 1 | |a London : |b Academic Press, |c 2021. | |
| 300 | |a 1 online resource : |b illustrations, chiefly color | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file | ||
| 347 | |b PDF | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a "Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, this reference allows readers to get started and establish a full workflow from the beginning of the project to its full completion. With worked examples drawn from real-life experiments, as well as troubleshooting and pitfalls to avoid, the book serves as an essential reference for researchers and investigators in both cardiovascular and biomedical research. Help readers familiarise with the variety of genome-editing approaches that are being applied in cardiovascular research and medicine, i.e., both research applications and clinical applications Understand the use of genome editing through worked examples (based on real-life experiments) in which CRISPR-Cas9 is employed, online tools to design CRISPR-Cas9 reagents, methods to interpret data from genome-editing experiments, the downsides of genome-editing technology - both the scientific and ethical pitfalls to avoid. Written in an easy-to-follow manner, guiding readers from the design of the project to its completion. Includes unpublished and new methods."--Provided by publisher | ||
| 505 | 0 | |a A brief history and primer on genome editing -- Choosing a genome editing strategy and target site -- Choosing a nuclease, guide RNA, and repair template -- Assessing the outcomes of genome editing -- Assessing for off-target mutagenesis -- Base editing -- Alternative types of editing -- Genome editing for cellular disease modeling -- Genome editing for functional experiments and screens -- Therapeutic genome editing. | |
| 588 | 0 | |a Online resource; title from resource home page (ProQuest Ebook Central, viewed October 13, 2021). | |
| 650 | 0 | |a Gene editing. | |
| 650 | 0 | |a CRISPR-associated protein 9. | |
| 650 | 0 | |a CRISPR (Genetics) | |
| 650 | 0 | |a Cardiovascular system |x Diseases |x Genetic aspects. | |
| 650 | 2 | |a Gene Editing |0 (DNLM)D000072669 | |
| 650 | 2 | |a CRISPR-Associated Protein 9 |0 (DNLM)D000076987 | |
| 650 | 2 | |a Clustered Regularly Interspaced Short Palindromic Repeats |0 (DNLM)D064112 | |
| 650 | 6 | |a �Edition g�enique. |0 (CaQQLa)000312026 | |
| 650 | 6 | |a Prot�eine-9 associ�ee �a CRISPR. |0 (CaQQLa)000311707 | |
| 650 | 6 | |a Appareil cardiovasculaire |0 (CaQQLa)201-0057760 |x Maladies |0 (CaQQLa)201-0057760 |x Aspect g�en�etique. |0 (CaQQLa)201-0377534 | |
| 650 | 6 | |a CRISPR (G�en�etique) |0 (CaQQLa)000340192 | |
| 650 | 7 | |a Cardiovascular system |x Diseases |x Genetic aspects |2 fast |0 (OCoLC)fst00847194 | |
| 650 | 7 | |a CRISPR-associated protein 9 |2 fast |0 (OCoLC)fst02000537 | |
| 650 | 7 | |a CRISPR (Genetics) |2 fast |0 (OCoLC)fst02000514 | |
| 650 | 7 | |a Gene editing |2 fast |0 (OCoLC)fst02000662 | |
| 776 | 0 | 8 | |i Print version: |a Musunuru, Kiran. |t Genome editing. |d London : Academic Press, 2021 |z 9780128234846 |w (OCoLC)1220993131 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128234846 |z Texto completo |