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|a The cancer stem cell niche /
|c edited by Susie Nilsson.
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|a Cambridge, MA :
|b Academic Press,
|c 2021.
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|a 1 online resource
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|a text
|b txt
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|a Advances in stem cells and their niches ;
|v volume 5
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0 |
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|a Intro -- The Cancer Stem Cell Niche -- Copyright -- Contents -- Contributors -- Chapter One: Acute lymphoblastic leukemia and the bone marrow microenvironment -- 1. Introduction -- 2. Cellular components of the ALL niche -- 2.1. Osteoblasts and osteoclasts -- 2.2. Mesenchymal stem/stromal cells (MSC) -- 2.3. Endothelial cells -- 2.4. Regulatory T-cells -- 2.5. Central nervous system (CNS) -- 3. Extracellular components of the ALL niche -- 3.1. Cytokines -- 3.2. Extracellular matrix (ECM) molecules -- 3.3. Oxygen/hypoxia/reactive oxygen species (ROS) -- 3.4. Metal ions -- 4. Summary
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|a Acknowledgments -- Conflicts of interest -- References -- Chapter Two: Stem cell niches in bone and their roles in cancer metastasis -- 1. Introduction -- 2. Niches within the bone marrow -- 3. Niche constituents originating from mesenchymal stem cells -- 3.1. Osteoblasts -- 3.2. Osteocytes -- 3.3. Bone marrow adipocytes -- 4. Niche constituents originating from hematopoietic stem cells -- 4.1. Osteoclasts -- 4.2. Immune cells -- 5. Other niche constituent cell types -- 5.1. Endothelial cells -- 5.2. Nerves -- 5.3. Megakaryocytes and platelets -- 6. Future perspectives -- References
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|a Chapter Three: The role of vasculature in cancer stem cell niches -- 1. Introduction -- 2. Niche functions of vasculature -- 3. Links between vasculature and cancer cell stemness -- 4. Angiocrine crosstalk in the tumor microenvironment -- 5. Maladaptation of vasculature in the tumor microenvironment -- 6. Vascular microenvironments supporting the cancer stem cell quiescence -- 7. Vascular niches for disseminated tumor cells and CSCs in the bone marrow -- 8. Conclusions -- References -- Chapter Four: The lung cancer stem cell niche -- 1. Introduction
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|a 2. Epithelial stem cell compartments in the adult lung -- 2.1. Developmental origins and regulation of the lung epithelial stem cell hierarchy -- 2.2. Stem and progenitor cells of the proximal airways -- 2.3. Stem and progenitor cells of the distal airways -- 2.4. Stem and progenitor cells of the alveolar bed -- 2.5. Lung stem and progenitor cell plasticity -- 2.6. Human lung stem cell homologs -- 3. Lung cancer stem cells -- 3.1. Non-small cell lung cancer -- 3.2. Small cell lung cancer -- 4. Deconstructing the lung cancer stem cell niche -- 4.1. Field of injury and field cancerization
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|a Stem cells.
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|a Cancer cells.
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|a Stem Cells
|0 (DNLM)D013234
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|a Cellules souches.
|0 (CaQQLa)201-0058821
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|a Cellules canc�ereuses.
|0 (CaQQLa)201-0022186
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|a Cancer cells.
|2 fast
|0 (OCoLC)fst00845563
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|a Stem cells.
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| 700 |
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|a Nilsson, Susie,
|e editor.
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0 |
8 |
|i Print version:
|z 0323853250
|z 9780323853255
|w (OCoLC)1201666474
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| 830 |
|
0 |
|a Advances in stem cells and their niches ;
|v volume 5.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/24685097/5
|z Texto completo
|
