Transport proteins /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Donev, Rossen
Formato: Electrónico eBook
Idioma:Inglés
Publicado: [Place of publication not identified] : Academic Press, 2021.
Colección:Advances in protein chemistry and structural biology ; v. 123.
Temas:
Carrier proteins.
Carrier Proteins
Prot�eines de liaison.
Carrier proteins
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Advances in Protein Chemistry and Structural Biology: Transport proteins
  • Advances in Protein Chemistry and Structural Biology: Transport proteins
  • Copyright
  • Contents
  • Contributors
  • One
  • Biology of the iron efflux transporter, ferroportin
  • 1. Iron metabolism and the central role of ferroportin
  • 1.1 Identification of ferroportin
  • 2. Structure of ferroportin
  • 3. Regulation of ferroportin
  • 4. Disorders associated with ferroportin dysfunction
  • 5. Ferroportin partners-molecules involved in efficient ferroportin functioning
  • 6. Conclusion
  • References
  • Two
  • The effect of sport and physical activity on transport proteins: implications for cancer prevention and control
  • 1. Transport proteins
  • 2. Muscles
  • 3. Muscle and transport proteins
  • 4. Sport and transport proteins: implications for cancer treatment and prevention
  • 5. Conclusions
  • References
  • Three
  • Cancer bioenergetics as emerging holistic cancer theory: the role of metabolic fluxes and transport protein ...
  • 1. Introduction
  • 2. Cancer and bio-energetics: the emerging field of "onco-energetics"
  • 3. Altered glycolysis and pyruvate oxidation metabolic fluxes in cancer
  • 4. Altered glutamine metabolic fluxes in cancer
  • 5. Altered serine metabolic fluxes in cancer
  • 6. Altered TCA metabolism in cancer
  • 7. Altered methionine metabolism in cancer
  • 8. Altered tryptophan metabolism in cancer
  • 9. Altered leucine metabolism in cancer
  • 10. Altered ornithine metabolism in cancer
  • 11. Altered proline metabolism in cancer
  • 12. Altered acetate metabolism in cancer
  • 13. Altered lipid metabolism in cancer
  • 14. Mitochondrial structural and functional impairment
  • 15. Tumor microenvironment
  • 16. Nuclear DNA genes mutations
  • 17. Cellular pathways mutations
  • 18. Conclusions and future prospects
  • References
  • Four
  • Investigating mutations at the hotspot position of the ERBB2 and screening for the novel lead compound to tr ...
  • 1. Introduction
  • 2. Materials and methods
  • 2.1 Database for prevalence mutations in breast cancer
  • 2.2 Pathogenicity and stability prediction tools
  • 2.3 Amino acid conservation analysis
  • 2.4 Lipinski's rule
  • 2.5 Molecular docking
  • 2.6 Protein dynamics simulation
  • 3. Results
  • 3.1 Mutation prevalence
  • 3.2 Pathogenicity and stability analysis
  • 3.3 Conservation analysis
  • 3.4 Protein dynamics simulations

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