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210119s2021 ne o 000 0 eng d |
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|a YDX
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|d OCLCO
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|a 020000994
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|a QH499
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|a 617.954
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| 245 |
0 |
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|a Organ repair and regeneration :
|b preserving organs in the regenerative medicine era /
|c edited by Giuseppe Orlando, Shaf Keshavjee.
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| 264 |
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1 |
|a Amsterdam :
|b Academic Press,
|c 2021.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
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|a Front Cover -- ORGAN REPAIR AND REGENERATION -- ORGAN REPAIR AND REGENERATIONPRESERVING ORGANS IN THE REGENERATIVE MEDICINE ERAEDITED BYGIUSEPPE ORLANDO, MD, PHDMARIE CURI ... -- Copyright -- Contents -- Contributors -- Foreword -- Preface -- 1 -- Ischemia-reperfusion injury -- Concepts and molecular mechanisms of ischemia reperfusion injury -- Fundamental concept of ischemia-reperfusion injury -- Causes of ischemia-reperfusion injury -- Reactive oxygen species in ischemia-reperfusion injury -- Cell death pathways in ischemia-reperfusion injury -- Necrosis and necroptosis -- Pyroptosis
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| 505 |
8 |
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|a Apoptosis and autophagy -- Danger signals: the link between cell death to inflammation -- Danger-associated molecular patterns -- Pattern recognition receptors -- DAMP and PRR interaction-cell signaling -- DAMP and PRR interaction-inflammasome formation -- Cellular inflammation in ischemia-reperfusion injury -- Innate immune response -- Adaptive immune response -- Ischemia-reperfusion injury in acute kidney injury and transplantation -- Acute kidney injury and delayed graft function-definitions and implications
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| 505 |
8 |
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|a Delayed graft function-an important subset of acute kidney injury in transplantation -- Clinical studies investigating ischemia-reperfusion injury in DGF and AKI -- Preclinical research in renal ischemia-reperfusion injury -- Renal IRI model-animal selection -- Renal IRI model-surgical considerations -- Renal IRI model-quantification and analysis -- Limitations of the histological scoring system-human and animal studies -- Additional application-pancreatic and islet IRI -- Future directions -- References -- 2 -- Machine perfusion for donor organ repair: from vision to everyday clinical practice
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| 505 |
8 |
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|a Strategies for donor pool expansion -- Machine perfusion and liver anatomy -- Machine perfusion -- Liver anatomy and histology for machine perfusion -- Extrahepatic vessels -- Liver parenchyma -- Biliary system -- Mechanisms of preservation injury and graft protection -- Ischemia/reperfusion injury -- Bile duct injury -- Sinusoidal endothelial injury -- Graft viability assessment -- Vascular resistance -- Damage markers -- Energy metabolism -- Bile examination -- Clinical practices of ex situ machine perfusion -- Episode zero -- HMP -- HOPE and DHOPE -- NMP -- Viability assessment
|
| 505 |
8 |
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|a Combined HOPE and NMP -- References -- 3 -- Assessing and reconditioning kidneys using normothermic machine perfusion -- Introduction -- Development of NMP for renal grafts -- Perfusion solutions -- Acellular perfusates -- Blood-based perfusates -- Clinical normothermic machine perfusion -- Quality assessment and conditioning -- Repair mechanisms and potential for reconditioning -- Ischemia reperfusion injury -- Reversal of ischemia reperfusion injury -- Future developments -- Conclusion -- References -- Further reading -- 4 -- Autologous cells for renal allograft repair -- Introduction
|
| 650 |
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0 |
|a Organs (Anatomy)
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| 650 |
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0 |
|a Regenerative medicine.
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| 650 |
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0 |
|a Electronic books.
|
| 650 |
|
2 |
|a Regenerative Medicine
|0 (DNLM)D044968
|
| 650 |
|
6 |
|a Organes.
|0 (CaQQLa)201-0055459
|
| 650 |
|
6 |
|a M�edecine r�eg�en�eratrice.
|0 (CaQQLa)201-0437307
|
| 650 |
|
6 |
|a Livres num�eriques.
|0 (CaQQLa)201-0160798
|
| 650 |
|
7 |
|a e-books.
|2 aat
|0 (CStmoGRI)aat300265554
|
| 650 |
|
7 |
|a Organs (Anatomy)
|2 fast
|0 (OCoLC)fst01048044
|
| 650 |
|
7 |
|a Regenerative medicine
|2 fast
|0 (OCoLC)fst01745494
|
| 700 |
1 |
|
|a Orlando, Giuseppe,
|d 1970-
|e editor.
|
| 700 |
1 |
|
|a Keshavjee, Shaf,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|z 9780128194522
|
| 776 |
0 |
8 |
|i Print version:
|z 9780128194515
|z 0128194510
|w (OCoLC)1222800775
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128194515
|z Texto completo
|
