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210117s2021 ne o 000 0 eng d |
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|a 020007536
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|a 9780128195635
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|a 0128195630
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|a (OCoLC)1231653461
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|a RC268.4
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|a 616.9940654
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|a Cancer :
|b oxidative stress and dietary antioxidants /
|c edited by Victor R. Preedy, Vinood B. Patel.
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250 |
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|a Second edition.
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264 |
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|a Amsterdam :
|b Academic Press,
|c 2021.
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|a 1 online resource
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|a text
|b txt
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|a computer
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|a online resource
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|a Intro -- Cancer: Oxidative Stress and Dietary Antioxidants -- Copyright -- Preface -- Contents -- Contributors -- Section A: Oxidative stress and cancer -- Chapter 1: Paraoxonases, oxidative stress, and breast cancer -- Introduction -- Functions and physiological roles of PON1 -- PON1 and cancer: Focusing on breast cancer -- PON1 signaling pathways -- PON1 polymorphisms -- Function and physiological roles of PON2 and PON3 -- PON2/3 and cancer: Focusing on breast cancer -- PON2 signaling pathways -- PON3 signaling pathways -- PON2/3 polymorphisms
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|a The paradox: PON activities and BC development -- Concluding remarks -- Application to other cancers -- Summary points -- References -- Chapter 2: Oxidative stress and prostate cancer -- Introduction -- Causes of oxidative stress in prostate cancer -- Increased ROS production -- Altered mitochondrial bioenergetics -- Upregulation of Nox enzymes -- Upregulation of COX enzymes -- Hypoxia -- Impaired antioxidant defenses -- Altered antioxidant enzymes -- Altered transcriptional factors related to the redox balance -- Role of oxidative stress in the pathogenesis of prostate cancer
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|a Oxidative stress in carcinogenesis and cancer progression -- Oxidative stress in castration resistance -- Oxidative stress in resistance to other therapeutics -- Prostate cancer risk factors and their links to oxidative stress -- Aging -- Genetic background (race and family history) -- Androgens -- Inflammation -- Diet -- Lifestyle -- Conclusions -- Applications to other cancers or conditions -- Summary points -- References -- Chapter 3: Oxidative stress in lung cancer -- Introduction -- Lung cancer -- Etiology of lung cancer -- Tobacco smoking -- Air pollution -- Infection and inflammation
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|a Radon -- Genetics -- Tobacco smoking and oxidants -- Silica and oxidants -- Asbestos and oxidants -- MicroRNAs and oxidative stress -- Radon and oxidative stress -- Inflammation and oxidative stress -- Oxidative stress leads to DNA mutations and lung cancer -- Lipid and protein peroxidation -- Antioxidants and lung cancer prevention -- Conclusion -- Summary points -- References -- Chapter 4: Endogenous antioxidants in the prognosis and treatment of lung cancer -- Double-edged sword of antioxidants in cancer -- Nrf2: Transcriptional regulator of the redox balance -- Role of Nrf2 -- Nrf2 in NSCLC
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|a Nrf2-mediated chemoresistance and therapeutic strategies -- Glutathione and thioredoxin antioxidant systems -- GSH system -- GSH system in NSCLC -- Therapeutic strategies -- Trx system -- Trx system in NSCLC -- Therapeutic strategies -- Dual targeting of the Trx and GSH systems -- Application to other cancers -- Summary points -- References -- Chapter 5: Oxidative stress in stomach cancer -- Introduction -- Oxidative stress and host cell -- Oxidative stress and H. pylori -- Host damage by oxidative stress and gastric carcinogenesis -- Oxidative stress and CD44v9-positive gastric cancer stem cells
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650 |
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|a Cancer
|x Molecular aspects.
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650 |
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|a Oxidative stress.
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650 |
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2 |
|a Oxidative Stress
|0 (DNLM)D018384
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650 |
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|a Cancer
|x Aspect mol�eculaire.
|0 (CaQQLa)201-0212614
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650 |
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|a Stress oxydatif.
|0 (CaQQLa)201-0352197
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650 |
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7 |
|a Cancer
|x Molecular aspects.
|2 fast
|0 (OCoLC)fst00845397
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650 |
|
7 |
|a Oxidative stress.
|2 fast
|0 (OCoLC)fst01049566
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700 |
1 |
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|a Preedy, Victor R.,
|e editor.
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700 |
1 |
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|a Patel, Vinood B.,
|e editor.
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776 |
0 |
8 |
|i Ebook version :
|z 9780128195635
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776 |
0 |
8 |
|i Print version:
|t Cancer.
|b Second edition.
|d Amsterdam : Academic Press, 2021
|z 9780128195475
|z 0128195479
|w (OCoLC)1222780217
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128195475
|z Texto completo
|