Advances in animal genomics /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Mondal, Sukanta, Singh, Ram Lakhan
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Animal genetics.
Genomics.
Genomics
G�en�etique animale.
G�enomique.
Animal genetics
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Advances in Animal Genomics
  • Advances in Animal Genomics
  • Copyright
  • Dedication
  • Contents
  • Contributors
  • Preface
  • KEY FEATURES OF THE BOOK
  • ORGANIZATION OF THE BOOK
  • Acknowledgments
  • 1
  • Introduction
  • 1.1 Introduction
  • 1.2 Branches of animal genomics
  • 1.2.1 Structural genomics
  • 1.2.2 Functional genomics
  • 1.2.3 Epigenomics
  • 1.2.4 Metagenomics
  • 1.2.5 Pharmacogenomics
  • 1.3 Genetic markers used in animal genomics
  • 1.3.1 Restriction fragment length polymorphism (RFLP)
  • 1.3.2 Random amplified polymorphic DNA (RAPD)
  • 1.3.3 Microsatellites
  • 1.3.4 Single nucleotide polymorphism (SNP)
  • 1.4 Techniques used in creating transgenic animals
  • 1.4.1 Microinjection
  • 1.4.2 Somatic cell nuclear transfer (SCNT)
  • 1.4.3 Artificial chromosome transfer
  • 1.4.4 Embryonic stem (ES) cell-based cloning and transgenesis
  • 1.4.5 Viral vector-mediated DNA transfer
  • 1.5 Application of animal genomics
  • 1.5.1 Livestock breeding industry
  • 1.5.2 Transgenic animal
  • 1.5.3 Gene therapy
  • 1.5.4 Superovulation
  • 1.5.5 Improving hair and fiber
  • 1.5.6 Disease resistant animals
  • 1.5.7 Nutritious food
  • 1.6 Conclusion
  • References
  • Further reading
  • 2
  • From gene to genomics: tools for improvement of animals
  • 2.1 Introduction
  • 2.2 Genes
  • 2.2.1 Chromosome structure and organization
  • 2.2.2 Gene structure and organization
  • 2.2.2.1 Eukaryotic gene
  • 2.2.2.2 Prokaryotic gene
  • 2.3 Genome
  • 2.3.1 Anatomy of the eukaryotic genome
  • 2.3.1.1 Gene and gene-related sequences
  • 2.3.1.1.1 Exons (protein-coding regions)
  • 2.3.1.1.2 Regulating sequences
  • 2.3.1.1.3 Introns
  • 2.3.1.1.4 Gene fragments
  • 2.3.1.1.5 Pseudogenes
  • 2.3.2 Sequencing genomes
  • 2.3.2.1 Shotgun approach
  • 2.3.2.2 Clone contig approach or clone by clone approach
  • 2.3.3 The methodology for DNA sequencing
  • 2.3.3.1 Chemical method (Maxam-Gilbert sequencing)
  • 2.3.3.2 Chain termination method or dideoxy method (Sanger's method)
  • 2.3.3.3 Next-generation sequencing (NGS) methods or high-throughput sequencing (HTS)
  • 2.3.4 The Human Genome Projects
  • 2.3.5 Genomic libraries
  • 2.3.6 cDNA libraries
  • 2.4 Genomics
  • 2.4.1 Types of genomics
  • 2.4.1.1 Structural
  • 2.4.1.2 Functional
  • 2.4.1.3 Comparative
  • 2.4.1.3.1 Exon shuffling
  • 2.4.1.3.2 Genome similarity
  • 2.4.1.3.3 Gene order comparison
  • 2.4.1.3.4 Horizontal gene transfer
  • 2.4.1.3.5 Single nucleotide polymorphisms (SNPs)
  • 2.4.1.3.6 Phylogenetic footprinting
  • 2.5 Evolution of animal genomics
  • 2.5.1 Mapping genomes
  • 2.5.1.1 Genetic mapping
  • 2.5.1.2 Physical mapping
  • 2.5.2 Regulation of gene expression
  • 2.5.2.1 Regulation of gene expression in eukaryotes
  • 2.5.2.1.1 Chromatin structure
  • 2.5.2.1.2 Initiation of transcription
  • 2.5.2.1.3 Post-transcriptional processing
  • 2.5.2.1.4 Initiation of translation
  • 2.5.2.1.5 Post-translational processing

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