Cargando…

Nanoformulation strategies for cancer treatment /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Beg, Sarwar, 1987-, Rahman, Mahfoozur, Choudhry, Hani, Souto, Eliana B., Ahmad, Farhan J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Elsevier, 2020.
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Nanoformulation Strategies for Cancer Treatment
  • Copyright Page
  • Contents
  • List of contributors
  • A. General consideration on cancer nanomedicines
  • 1 Nanomedicine for combinational anticancer drug therapeutics: Recent advances, challenges, and future perspectives
  • 1.1 Introduction
  • 1.2 Various barriers to overcome in cancer treatment
  • 1.3 Combinational anticancer therapeutic approach
  • 1.3.1 Polyplexes
  • 1.3.2 Liposomes
  • 1.3.3 Micelles
  • 1.3.4 Dendrimers
  • 1.3.5 Host-guest supramolecular chemistry
  • 1.3.6 Inorganic systems
  • 1.3.7 Other dual-drug delivery systems
  • 1.4 Conclusions and future perspectives
  • References
  • 2 Market research in cancer therapeutics: New and generic product development
  • 2.1 Introduction
  • 2.2 Cancer therapeutics
  • 2.3 Prevention
  • 2.4 Early detection and screening
  • 2.5 Diagnosis and treatment
  • 2.6 Overall strategies
  • 2.7 New and generic product development in the pharmaceutical industry
  • 2.8 Developing a plan for marketing and selling specialist therapies
  • 2.9 Creating a marketing and sales function that is fit for the future
  • 2.10 Conclusions and future perspectives
  • 4 Biopharmaceutical challenges in using lipid nanoparticles for oral chemotherapy
  • 4.1 Introduction
  • 4.2 Biopharmaceutical chemotherapy obstacles
  • 4.3 Lipid nanoparticles for oral cancer chemotherapy
  • 4.3.1 Rationale
  • 4.3.2 Recent developments
  • 4.3.3 Solid lipid nanoparticles
  • 4.3.4 Nanostructured lipid carriers
  • 4.3.5 Lipid-drug conjugates
  • 4.4 Pharmacokinetics of lipid nanoparticles
  • 4.4.1 Biodistribution
  • 4.4.2 Metabolism and elimination
  • 4.5 Future recommendations and conclusion
  • References
  • Further reading
  • 5 Polymeric nanoparticles for potential drug delivery applications in cancer
  • 5.1 Introduction
  • 5.2 Rationale to use polymeric nanoparticles in cancer therapy
  • 5.3 Advantages of polymeric nanoparticles
  • 5.4 Disadvantages of polymeric nanoparticles
  • 5.5 Factors considered during the development of nanoformulations
  • 5.6 Polymers used for polymeric nanoparticles
  • 5.6.1 Natural hydrophilic polymers
  • 5.6.2 Synthetic hydrophobic polymer
  • 5.7 Mechanisms of nanoparticles uptake by the cancer cells
  • 5.7.1 Targeting of polymeric nanoparticles to cancer cells
  • 5.7.1.1 Passive targeting