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|d OPELS
|d OCLCO
|d EBLCP
|d OCLCF
|d OCLCO
|d OCLCQ
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|a 9780128218235
|q (electronic bk.)
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|a 0128218231
|q (electronic bk.)
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|z 9780128218228
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|z 0128218223
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|a (OCoLC)1224004547
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|a QH603.C43
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|a 572.696
|2 23
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|a TAM receptors in health and disease /
|c edited by Viralkumar Davra, Lorenzo Galluzzi.
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|a Cambridge, MA :
|b Academic Press,
|c 2020.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a International review of cell and molecular biology ;
|v v. 357
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|a Print version record.
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|a Intro -- TAM Receptors in Health and Disease -- Copyright -- Contents -- Contributors -- Chapter One: Recent advancements in role of TAM receptors on efferocytosis, viral infection, autoimmunity, and tissue repair -- 1. Introduction -- 2. Discovery of TAM receptors -- 3. Overview of TAM receptors signaling -- 4. Role of TAM receptors in viral infections -- 5. Implication of TAM receptors in efferotyosis of ``DEAD�� cells -- 6. New understanding of TAM receptors in autoimmunity -- 7. Tissue repair emerges as a newly defined function of TAM receptors -- References
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|a Chapter Two: TAM receptors and their ligand-mediated activation: Role in atherosclerosis -- 1. Introduction -- 2. Defective efferocytosis and inflammation resolution in atherosclerosis -- 2.1. Defective efferocytosis in atherosclerosis -- 2.2. Defective inflammation resolution in atherosclerosis -- 2.3. MerTK-mediated efferocytosis and inflammation resolution -- 2.4. MerTK cleavage by ADAM17 -- 3. Conclusions and future directions -- Acknowledgments -- References -- Chapter Three: Post-translational modifications of the ligands: Requirement for TAM receptor activation
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|a 1. Overview of TAM receptors -- 2. TAM receptors� biological functions -- 2.1. Efferocytosis -- 2.2. Regulation of innate immune response -- 2.3. Promoting cancer development -- 3. Ligand proteins for TAM receptors -- 4. Post-translational modifications regulate Gas6/Pros1 activity -- 5. Phosphatidylserine (PtdSer) and the mechanisms of PtdSer externalization -- 6. Concluding remarks -- References -- Chapter Four: Immunological role of TAM receptors in the cancer microenvironment -- 1. Introduction -- 2. Oncogenic functions of TAM receptors -- 3. Immune regulation in the tumor microenvironment
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|a 4. Role of TAM receptors in the innate immunity -- 5. Role of TAM receptors in the adaptive immunity -- 6. Role of TAM receptors in the tumor microenvironment -- 7. Role of TAM receptor ligands in cancer -- 8. Targeting TAM receptors in cancer -- 8.1. Classical small molecule tyrosine kinase inhibitors -- 8.2. Antagonistic therapeutic antibodies -- 8.3. Ligand targeted blockade: Soluble ectodomain receptors, a.k.a. ``decoy receptors,�� and Vitamin-K antagonists -- 9. Concluding remarks and summary -- References
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|a Chapter Five: TAM receptors: A phosphatidylserine receptor family and its implications in viral infections -- 1. Introduction -- 1.1. Phosphatidylserine -- 1.2. TAM receptor family -- 2. TAM receptors in viral infection -- 2.1. Negative-sense ssRNA viruses -- 2.1.1. Mononegavirales (order) -- 2.1.1.1. Filoviridae (family) -- 2.1.1.1.1. Ebola and Marburg -- 2.1.1.2. Pneumoviridae (family) -- 2.1.1.2.1. Human orthopneumovirus (Respiratory syncytial virus/RSV) -- 2.1.1.3. Rhabdoviridae (family) -- 2.1.1.3.1. Vesicular stomatitis virus (VSV) -- 2.1.2. Articulavirales (order)
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|a Cell receptors
|x Health aspects.
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| 650 |
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|a Amines in the body.
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6 |
|a Amines dans l'organisme.
|0 (CaQQLa)201-0002442
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| 650 |
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7 |
|a Amines in the body
|2 fast
|0 (OCoLC)fst00807605
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| 700 |
1 |
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|a Davra, Viralkumar.
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| 700 |
1 |
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|a Galluzzi, Lorenzo.
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| 776 |
0 |
8 |
|i Print version:
|t TAM receptors in health and disease.
|d Cambridge, MA : Academic Press, 2020
|z 0128218223
|z 9780128218228
|w (OCoLC)1154090216
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| 830 |
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0 |
|a International review of cell and molecular biology ;
|v v. 357.
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| 856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/bookseries/19376448/357
|z Texto completo
|
