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Influence of nutrients, bioactive compounds and plant extracts in liver diseases /

Influence of Nutrients, Bioactive Compounds, and Plant Extracts in Liver Diseases provides evidence-based knowledge of the mechanism of action of natural compounds, as well as the relation of structure and function of phytochemicals in hepatitis B and C, fatty liver disease, nonalcoholic fatty liver...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alavian, Seyed Moayed
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2021.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Influence of Nutrients, Bioactive Compounds and Plant Extracts in Liver Diseases
  • Copyright
  • Dedication
  • Contents
  • Contributors
  • Preface
  • Chapter 1 Introduction
  • References
  • Part 1 Hepatoprotective activity of natural compounds and plant extracts in liver diseases
  • Chapter 2 Hepatitis B
  • 2.1 Introduction
  • 2.2 Rheum palmatum L.
  • 2.3 Ganoderma lucidum (Curtis) P. Karst.
  • 2.4 Oenanthe javanica (Blume) DC.
  • 2.5 Curcuma longa L.
  • 2.6 Phyllanthus amarus Schum. and Thonn.
  • 2.7 Phyllanthus niruri L.
  • 2.8 Swertia patens Burkill
  • 2.9 Boehmeria nivea (L.) Gaudich.
  • 2.10 Role of natural compounds in ameliorating hepatitis B
  • 2.10.1 Terpenoids
  • 2.10.2 Lignans
  • 2.10.3 Phenolic acids
  • 2.10.4 Polyphenols
  • 2.10.5 Alkaloids
  • 2.11 Conclusion
  • Acknowledgments
  • Conflict of interest
  • References
  • Further reading
  • Chapter 3 Hepatitis C
  • 3.1 Introduction
  • 3.2 Etiology
  • 3.3 Signs and symptoms
  • 3.4 Genotypes and serotypes of HCV
  • 3.5 Diagnosis (serology, biopsy, and screening)
  • 3.6 Serology
  • 3.7 Screening tests
  • 3.7.1 Enzyme immunosorbent assay (EIA)
  • 3.7.2 The rapid test (point of care test)
  • 3.7.2.1 Confirmatory tests
  • 3.8 Biopsy
  • 3.9 Screening
  • 3.10 Prevention
  • 3.11 Treatment
  • 3.12 Hepatoprotective activity of natural compounds and plant extracts in Hepatitis C
  • 3.12.1 Silymarin
  • 3.12.2 Naringenin
  • 3.12.3 Quercetin
  • 3.12.4 ( )-Epigallocatechin-3-gallate (EGCG)
  • 3.12.5 Luteolin and apigenin
  • 3.12.6 Honokiol
  • 3.12.7 3-Hydroxy caruilignan C (3-HCL-C)
  • 3.12.8 Ladanein
  • 3.12.9 Plumbagin
  • 3.12.10 Corilagin
  • 3.13 Conclusion
  • Conflict of interest
  • References
  • Chapter 4 Alcoholic liver disease
  • 4.1 Introduction
  • 4.2 The cause and consequences of alcohol toxicity.
  • 4.2.1 Alcohol metabolism and oxidative stress
  • 4.2.2 Genetic alterations in developing of alcoholic liver diseases
  • 4.2.3 The role of cytokines, chemokines, and adipocytokines in alcoholic liver disease
  • 4.2.4 Sex differences in alcohol sensitivity
  • 4.3 Alcohol as a depressant
  • 4.4 Complex treatment of alcohol disease
  • 4.4.1 Treatment of alcoholic liver diseases with vitamin supplements, nutrition, and medicaments with natural ingredi ...
  • 4.4.2 Some traditional herbal medicines in complex treatment of alcoholists: Favorable and adverse effects
  • 4.4.2.1 Hypericum perforatum L. (St. John's wort)
  • 4.4.2.2 Pueraria lobate Willd. (Ohwi kudzu)
  • 4.4.2.3 Salvia miltiorrhiza Bge. (Danshen)
  • 4.4.2.4 Tabernanthe iboga H. Bn. (Ibogaine)
  • 4.4.2.5 Panax ginseng C.A. Mey. (Ginseng)
  • 4.4.2.6 Piper methysticum G. Forst. (Kava)
  • 4.4.2.7 Morus nigra L. (mulberry) and Taraxacum coreanum Nakai (dandelion)
  • 4.4.2.8 Hovenia dulcis Thunb. (Japanese raisin tree)
  • 4.5 Conclusions
  • References
  • Chapter 5 Hepatoprotective activity of natural compounds and plant extracts in nonalcoholic fatty liver disease
  • 5.1 Introduction
  • 5.2 Nonalcoholic fatty liver disease pathogenesis and progression
  • 5.3 Oxidative stress and lipotoxicity
  • 5.4 Mediterranean diet and nonalcoholic fatty liver disease
  • 5.5 Natural compound effects on nonalcoholic fatty liver disease
  • 5.6 Conclusions
  • Acknowledgments
  • References
  • Chapter 6 Liver cancer
  • 6.1 Introduction
  • 6.2 Classification of hepatic cancers
  • 6.2.1 Benign tumors
  • 6.2.2 Malignant tumors
  • 6.3 Causes of liver cancer
  • 6.4 Diagnosis
  • 6.4.1 Nuclear medical imaging
  • 6.4.2 Single photon emission computed tomography (SPECT)
  • 6.4.3 Liver puncture biopsy
  • 6.4.4 Serological molecular markers for liver cancer.
  • 6.4.5 Pathological diagnosis of liver cancer
  • 6.4.6 Prevention
  • 6.4.7 Treatment
  • 6.4.7.1 Glycyrrhizin
  • 6.4.7.2 Wogonin
  • 6.4.7.3 Resveratrol
  • 6.4.7.4 Curcumin
  • 6.4.7.5 Silymarin
  • 6.4.7.6 Rhein
  • 6.4.7.7 Naringenin
  • 6.4.7.8 Geniposide
  • 6.4.7.9 Salvianolic acid B (or magnesium lithospermate B, SAB)
  • 6.4.7.10 Oxymatrine (or kwoninone, OM)
  • 6.4.7.11 Tetrandrine
  • 6.4.7.12 Berberine
  • 6.4.7.13 Others
  • 6.5 Conclusion
  • Conflict of interest
  • References
  • Chapter 7 Chronic liver diseases
  • 7.1 Introduction
  • 7.2 Primary sclerosing cholangitis
  • 7.3 Hepatic steatosis
  • 7.4 Primary biliary cirrhosis
  • 7.5 Liver fibrosis
  • 7.6 The use of bioactive compounds and plant extracts in chronic liver diseases
  • 7.7 Nutritional support in CLD
  • References
  • Chapter 8 Drug-induced hepatotoxicity
  • 8.1 Background
  • 8.2 Hepatotoxicity: An overview
  • 8.3 Drug metabolic pathways of the liver and hepatotoxicity
  • 8.4 Drug-induced hepatotoxicity: Mechanisms and risk factors
  • 8.5 Epidemiological aspects
  • 8.6 Hepatoprotective activity of natural compounds and plant extracts in drug-induced hepatotoxicity
  • 8.7 Conclusion
  • References
  • Part 2 Influence of nutrients, plant extracts and natural compounds in liver diseases
  • Chapter 9 Influence of omega-3 fatty acids and monounsaturated fats in liver diseases
  • 9.1 Introduction
  • 9.2 Chemistry and classification of omega fatty acids
  • 9.3 Conversion of ALA to EPA and DHA
  • 9.4 Chemistry and classification of MUFA
  • 9.5 Sources of omega-3 fatty acids and MUFAs
  • 9.6 Metabolism of omega-3 fatty acids and monounsaturated fats
  • 9.7 Role of omega-3 fatty acids and monounsaturated fats in various liver diseases
  • 9.7.1 Nonalcoholic fatty liver disease (NAFLD)
  • 9.7.2 Nonalcoholic steatohepatitis (NASH)
  • 9.7.3 Fibrosis.
  • 9.7.4 Hepatocellular carcinoma (HCC)
  • 9.8 Conclusion
  • Conflict of interest
  • References
  • Chapter 10 Influence of vitamins (C, B 3, D, and E) in liver health
  • 10.1 Introduction
  • 10.2 Vitamin C
  • 10.3 Vitamin B 3 (niacin)
  • 10.4 Vitamin D
  • 10.5 Vitamin E
  • 10.6 Vitamin combinations and liver health
  • 10.7 Conclusion
  • References
  • Chapter 11 Influence of other nutrients (e.g., l -arginine, taurine, and choline) on liver diseases
  • 11.1 Introduction
  • 11.2 Liver diseases
  • 11.3 Arginine
  • 11.3.1 Structural characteristics and metabolism
  • 11.3.2 Functional links with the liver
  • 11.3.3 Evidence of hepatoprotective functions
  • 11.4 Taurine
  • 11.4.1 Chemical structure and biological functions
  • 11.4.2 Potential effects as a therapeutic agent
  • 11.4.3 Clinical studies linked to liver diseases
  • 11.5 Choline
  • 11.5.1 Its metabolites and dietary sources
  • 11.5.2 Aspects of its metabolism
  • 11.5.3 Clinical evidence of the effect on liver health
  • 11.6 Conclusions
  • References
  • Chapter 12 Antioxidants with hepatoprotective activity
  • 12.1 Introduction
  • 12.2 Natural hepatoprotective agents
  • 12.2.1 Ursodeoxycholic acid
  • 12.2.2 Choline
  • 12.2.3 Betaine
  • 12.2.4 S -Adenosyl- l -methionine
  • 12.2.5 Melatonin
  • 12.2.6 Glutathione
  • 12.2.7 N -Acetylcysteine
  • 12.2.8 Minerals in antioxidant enzymes
  • 12.2.9 Vitamins E and C
  • 12.2.10 Lycopene
  • 12.2.11 Beta-carotene
  • 12.2.12 Silymarin
  • 12.2.13 Alpha-lipoic acid
  • 12.2.14 Coenzyme Q10
  • 12.2.15 Curcumin
  • 12.2.16 Other natural antioxidants with hepatoprotective effects
  • 12.3 Synthetic hepatoprotectors with antioxidant activity
  • 12.3.1 Pentoxiyfylline
  • 12.3.2 Angiotensin-converting enzyme inhibitors
  • 12.4 Conclusion
  • References
  • Chapter 13 Plant extracts with putative hepatoprotective activity.
  • 13.1 Introduction
  • 13.2 Conclusion
  • References
  • Chapter 14 Plant extracts with putative hepatotoxicity activity
  • 14.1 Introduction
  • 14.2 General concepts of hepatotoxicity
  • 14.2.1 Types of hepatotoxicity
  • 14.2.1.1 Idiosyncratic form of liver injury
  • 14.2.1.2 Intrinsic form of liver injury
  • 14.2.2 Causes of hepatotoxicity
  • 14.2.2.1 Hepatotoxicity induced by drugs
  • 14.2.2.2 Hepatotoxicity induced by viruses
  • 14.2.3 Mechanisms of hepatotoxicity
  • 14.2.3.1 Bile acid accumulation
  • 14.2.3.2 Activation of parenchymal cells
  • 14.2.3.3 Activation of nonparenchymal cells
  • 14.3 Hepatotoxicity induced by plant extracts and mushrooms
  • 14.3.1 Atractylis gummifera L.
  • 14.3.2 Morinda citrifolia L.
  • 14.3.3 Camellia sinensis L.
  • 14.3.4 Aloe vera L.
  • 14.3.5 Teucrium chamaedrys L.
  • 14.3.6 Chelidonium majus L.
  • 14.3.7 Piper methysticum G. Forst
  • 14.3.8 Larrea tridentata (Sess. & amp
  • Moc. ex DC.) Cov.
  • 14.3.9 Mentha pulegium L.
  • 14.3.10 Amanita phalloides (Vaill. ex Fr.: Fr.)
  • 14.3.11 Viscum album L.
  • 14.3.12 Xanthium strumarium L.
  • 14.3.13 Scutellaria biacalensis Georgi
  • 14.3.14 Callilepis laureola DC.
  • 14.3.15 Valeriana officinalis L.
  • 14.3.16 Hypericum perforatum L.
  • 14.3.17 Cascara sagrada DC.
  • 14.3.18 Cassia acutifolia Delile
  • 14.3.19 Actaea racemosa L.
  • 14.3.20 Echinaceae purpurea L.
  • 14.4 Conclusion
  • Acknowledgments
  • References
  • Index.