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|a UKAHL
|b eng
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|d OPELS
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|a 019949177
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|a 0128192631
|q (e-book)
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|a 9780128192634
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|z 9780128192627
|q (pbk.)
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|a (OCoLC)1223026058
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|a 155.7
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|a Developmental human behavioral epigenetics :
|b principles, methods, evidence, and future directions /
|c edited by Livio Provenzi, Rosario Montirosso.
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|a Amsterdam :
|b Academic Press,
|c 2020.
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Translational epigenetics ;
|v 23
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|a Intro -- Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions -- Copyright -- Contents -- Contributors -- Keeping complexity in mind -- References -- Section I: Introduction -- Chapter 1: Principles of epigenetics and DNA methylation -- Definition of epigenetics -- Types of epigenetic modifications -- DNA cytosine methylation -- DNA cytosine hydroxymethylation -- DNA adenosine methylation -- RNA modifications -- Histone modifications -- RNAs -- Environmental effects, cell metabolism and epigenetics -- Epigenetic memory -- Environmental effects
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|a Cell metabolism, diet and microbiota -- Methods for methylation analysis -- Chromatin immunoprecipitation -- Nucleosome positioning -- DNA cytosine methylation analysis -- Locus-specific DNA methylation analysis -- Whole methylome analysis -- Selected genome-wide methylation analysis -- Epigenotyping arrays -- Direct readout of DNA methylation -- DNA methylation analysis of cell-free circulating DNA -- Single-cell epigenomics -- References -- Chapter 2: From animal to human epigenetics -- A rat story: Behavioral epigenetics beginnings
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|a Post-natal maternal environment shapes the epigenome and adult behavioral phenotypes of the offspring -- Environmental stimuli delivered to parents trigger processes to transmit information to offspring -- Permissive environments -- Environmental enrichment -- Maternal enrichment during pregnancy and/or lactation -- Pre-reproductive parental enrichment -- Aversive environments -- Aversive environment: Animal studies -- Epigenetic perturbation can be passed along -- Combining human and non-human animal research -- References -- Chapter 3: An overview of developmental behavioral genetics
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|a Background/history -- Behavioral genetic methodology -- Key interpretative issues -- Key results from twin and adoption studies -- Gene-environment interplay -- Gene-environment correlation -- Passive rGE -- Active rGE -- Evocative rGE -- Gene-environment interaction -- Genomic approaches to behavioral genetics -- Concluding remarks -- References -- Section II: Behavioral epigenetics in action -- Chapter 4: Prenatal exposures and behavioral epigenetics in human infants and children -- Early environmental programming -- Biological embedding
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|a Fetal DNA methylation after exposure to prenatal stress -- Does DNA methylation at birth predict postnatal outcomes? -- Further directions -- References -- Chapter 5: Applying behavioral epigenetic principles to preterm birth and early stress exposure -- Introduction -- Background -- Epigenetic regulation by early adverse experiences -- Epigenetic regulation by early protective experiences -- Preterm birth and NICU-related early adverse experiences -- Preterm birth and NICU-related early protective experiences -- A rationale for preterm behavioral epigenetics -- State of the art of PBE research
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|a Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy. Enables more effective study design and methods application in behavioral epigenetics research across human and animal models Examines findings in human behavioral epigenetics to-date Features contributions from leading international researchers in behavioral epigenetics.
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520 |
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|a "Enables more effective study design and methods application in behavioral epigenetics research across human and animal models. Examines findings in human behavioral epigenetics to-date. Features contributions from leading international researchers in behavioral epigenetics"--
|c Provided by publisher.
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650 |
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0 |
|a Behavior genetics.
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650 |
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0 |
|a Epigenetics.
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650 |
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2 |
|a Genetics, Behavioral
|0 (DNLM)D005824
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650 |
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6 |
|a G�en�etique du comportement.
|0 (CaQQLa)201-0053262
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650 |
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6 |
|a �Epig�en�etique.
|0 (CaQQLa)000270630
|
650 |
|
7 |
|a Behavior genetics
|2 fast
|0 (OCoLC)fst00829913
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650 |
|
7 |
|a Epigenetics
|2 fast
|0 (OCoLC)fst01893642
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700 |
1 |
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|a Provenzi, Livio,
|e editor.
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700 |
1 |
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|a Montirosso, Rosario,
|e editor.
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776 |
0 |
8 |
|i Print version :
|z 9780128192627
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128192627
|z Texto completo
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