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Glaucoma : a neurodegenerative disease of the retina and beyond. Part B /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Walsh, Vincent, 1961- (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands : Elsevier, 2020.
Colección:Progress in brain research ; v. 257.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Glaucoma: A Neurodegenerative Disease of the Retina and Beyond
  • Part B
  • Copyright
  • Contributors
  • Contents
  • Preface
  • Chapter 1: Glaucoma neurodegeneration and myopia
  • 1. Introduction
  • 2. Optic nerve head
  • 3. Peripapillary ring
  • 4. Peripapillary scleral flange
  • 5. Peripapillary border tissues
  • 6. Peripapillary arterial circle of Zinn-Haller
  • 7. Parapapillary alpha, beta, gamma and delta zones
  • 8. Clinical diagnosis of glaucoma in high myopia
  • 9. Differential diagnosis of optic nerve damage in high myopia
  • 10. Myopic macular changes with respect to glaucoma
  • 11. Mechanisms potentially involved in the process of axial elongation leading to the myopic changes in the optic nerve head
  • 12. Conclusion
  • Funding
  • Financial interest
  • References
  • Chapter 2: Links between obstructive sleep apnea and glaucoma neurodegeneration
  • 1. Introduction
  • 2. Definition
  • 3. Diagnosis
  • 4. Risk factors, clinical presentation and therapeutic options
  • 5. Association between obstructive sleep apnea syndrome and glaucoma in adults
  • 6. Prevalence of glaucoma in patients with OSAS
  • 7. Pathogenesis
  • 7.1. Hypoxia and hypercapnia
  • 7.2. Vascular changes
  • 7.3. Mechanical factors
  • 8. Anatomical and functional findings
  • 9. Conclusions
  • References
  • Chapter 3: Artificial intelligence and deep learning in glaucoma: Current state and future prospects
  • 1. Introduction
  • 2. AI to better assess optic nerve head structure
  • 3. AI for glaucoma diagnosis
  • 4. AI for glaucoma prognosis
  • 5. AI for cost-effective screening
  • 6. AI and genetics in glaucoma
  • 7. Discussion
  • Acknowledgments
  • Support
  • References
  • Chapter 4: Brain networks reorganization and functional disability in glaucoma
  • Keywords
  • 1. Introduction
  • 2. Brain involvement in glaucoma: Histological and neuroimaging evidence
  • 3. Cerebral neurofunctional alterations and disabilities in glaucoma
  • 4. Conclusions
  • Disclosure statement
  • References
  • Chapter 5: Advanced vascular examinations of the retina and optic nerve head in glaucoma
  • References
  • Chapter 6: Evaluation of putative differences in vessel density and flow area in normal tension and high-pressure glaucoma us
  • 1. Introduction
  • 2. Materials and methods
  • 3. Statistical analysis
  • 4. Results
  • 5. Discussion
  • Acknowledgments
  • Conflicts of interest
  • Funding
  • References
  • Chapter 7: Towards stem cell-based neuronal regeneration for glaucoma
  • 1. Introduction
  • 2. RGC degeneration in glaucoma
  • 3. RGC regeneration
  • 3.1. ESC-derived RGCs
  • 3.2. iPSC-derived RGCs
  • 3.3. M�uller glia in RGC regeneration
  • 3.4. MSCs in RGC regeneration
  • 4. Purification and transplantation of stem cell-derived RGCs
  • 5. Other source cells
  • 6. Perspectives
  • References
  • Chapter 8: Naturally occurring neuroprotectants in glaucoma
  • 1. Introduction