Tabla de Contenidos:
  • Front Cover
  • Neural Regenerative Nanomedicine
  • Copyright Page
  • Contents
  • List of Contributors
  • Preface
  • 1 Advances and challenges toward neural regenerative medicine
  • 1.1 Introduction
  • 1.1.1 Blood-brain barrier
  • 1.1.1.1 Transport pathways across the blood-brain barrier
  • 1.1.1.2 Regulating the permeability of blood-brain barrier
  • 1.1.1.3 Challenges of blood-brain barrier
  • 1.1.1.4 Future of blood-brain barrier studies
  • 1.1.2 Other barriers
  • 1.2 Brain disorders
  • 1.2.1 Neurodegenerative disease
  • 1.2.1.1 Alzheimer disease
  • 1.2.1.2 Parkinson disease
  • 1.2.1.3 Multiple sclerosis
  • 1.2.1.4 Huntington disease
  • 1.2.2 Other brain disorders
  • 1.2.2.1 Brain cancer
  • 1.2.2.2 Spinal cord injury
  • 1.2.2.3 Stroke
  • 1.3 Novel treatment methods
  • 1.3.1 Intranasal technique
  • 1.3.2 Neurostem cell therapy
  • 1.3.3 Nanotechnology
  • 1.3.4 Nanomedicine
  • 1.3.4.1 Nanomedicine for imaging and tracing biomarkers
  • 1.3.4.2 Nanomedicine for diagnostic
  • 1.3.4.3 Nanomedicine for therapy
  • 1.3.4.4 Neurotoxicity of nanomedicine
  • 1.4 Conclusions and perspective
  • References
  • 2 Nanobiomaterials for neural regenerative medicine
  • 2.1 Conductive materials for nerve regeneration
  • 2.1.1 Conductive materials
  • 2.1.2 Synthesis and applications of conductive polymers
  • 2.1.3 Piezoelectric polymers
  • 2.2 Carbon-based nanobiomaterials
  • 2.2.1 Carbon nanotubes
  • 2.2.2 Nanodiamonds
  • 2.2.3 Graphene
  • 2.2.4 Fullerene
  • 2.2.5 Carbon quantum dots
  • 2.3 Polymeric nanobiomaterials
  • 2.3.1 Chitosan
  • 2.3.2 Collagen
  • 2.3.3 Gelatin
  • 2.3.4 Other polymers
  • 2.3.4.1 Hyaluronic acid
  • 2.3.4.2 Alginate
  • 2.3.4.3 Keratins
  • 2.3.4.4 Silk
  • 2.3.4.5 Synthetic polymers
  • 2.4 Self-assembling nanobiomaterials
  • 2.4.1 Guided assembly
  • 2.4.2 Direct assembly
  • 2.5 Metallic nanobiomaterials
  • 2.6 Summary and future
  • References
  • 3 Nanoscaffolds for neural regenerative medicine
  • 3.1 Introduction
  • 3.2 Micro- and nanofabrication techniques of 2D and 3D scaffolds
  • 3.2.1 Nanorough silicon surfaces
  • 3.2.2 Nanoporous and mesoporous silicon surfaces
  • 3.2.3 Arrays of zinc oxide nanowires
  • 3.2.4 PDMS substrates for cell growth and proliferation
  • 3.2.5 Superhydrophobic micropillars with lateral indentations
  • 3.2.6 Superhydrophobic PDMS micropillars
  • 3.2.7 3D scaffolds
  • 3.2.7.1 Solvent casting/particle leaching
  • 3.2.7.2 Gas foaming
  • 3.2.7.3 Phase separation
  • 3.2.7.4 Freeze drying
  • 3.2.7.5 Molding
  • 3.2.7.6 Nonwoven knitted and braided textiles
  • 3.2.7.7 Electrospinning
  • 3.2.7.8 Additive manufacturing
  • 3.2.7.9 Direct writing and extrusion
  • 3.2.7.10 Inkjet/powder systems (3D printing)
  • 3.2.7.11 Stereolithography
  • 3.2.7.12 Two-photon polymerization
  • 3.2.7.13 Selective laser sintering
  • 3.2.8 Chemical functionalization of scaffolds
  • 3.3 Characterization of micro- and nanofabricated scaffolds
  • 3.4 Elements of network analysis