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SCIDIR_on1176322227 |
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OCoLC |
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20231120010502.0 |
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m o d |
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200721s2020 ne o 001 0 eng d |
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|a YDX
|b eng
|e pn
|c YDX
|d OPELS
|d EBLCP
|d UKAHL
|d OCLCF
|d N$T
|d OCLCO
|d COM
|d OCLCO
|d OCLCQ
|d K6U
|d OCLCQ
|d OCLCO
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| 019 |
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|a 1176512063
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|a 9780128163740
|q (electronic bk.)
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|a 0128163747
|q (electronic bk.)
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|z 9780128159231
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| 020 |
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|z 0128159235
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| 035 |
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|a (OCoLC)1176322227
|z (OCoLC)1176512063
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4 |
|a RC902
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| 082 |
0 |
4 |
|a 616.61075
|2 23
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| 245 |
0 |
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|a Kidney biomarkers :
|b clinical aspects and laboratory determination /
|c edited by Seema S. Ahuja, Brian Castillo.
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| 260 |
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|a Amsterdam :
|b Academic Press,
|c 2020.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 500 |
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|a Includes index.
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| 505 |
8 |
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|a Further reading -- Chapter 2: Utility of the ``omics�� in kidney disease: Methods of analysis, sampling considerations, and technical approa ... -- Introduction -- Statistical methods in analysis and interpretation of biomarkers in kidney disease -- Metrics for prediction performance (diagnostic potential) -- Quantification of prediction performance -- True positive rate and false positive rate -- Receiver-operating characteristic curve -- Summary indices -- Area under the ROC curve (AUC) -- Optimal prediction threshold -- Partial area under the curve
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| 505 |
8 |
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|a Limitations of statistical metrics used for prediction performance -- Metrics to evaluating incremental diagnostic value -- Incremental value: How to evaluate? -- Improvement in discrimination -- Improvement in reclassification -- Net reclassification improvement -- Categorical net reclassification improvement -- Weighted net reclassification improvement -- Category-free net reclassification improvement -- Integrated discrimination improvement -- Decision and clinical use of analytic measures -- Recommendations for sample collection, storage, and preparation -- Tissue samples -- Biofluids
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| 505 |
8 |
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|a Nontargeted versus targeted analysis -- Proteomics and metabolomics in nephrology -- Potential impact of proteomics and metabolomics in renal diseases -- Proteomics and the kidney -- The proteomics sample -- Urine -- Kidney tissue and cell culture -- Techniques used in proteome analysis -- Proteomics methods based on mass spectrometry -- First step: Protein separation -- Gel-based proteome analysis -- Gel-free proteome analysis -- Liquid chromatography (LC) -- Capillary electrophoresis -- Second step: Protein identification
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| 505 |
8 |
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|a Two-dimensional gel electrophoresis coupled with mass spectrometry (2DE-MS) -- Liquid chromatography coupled to mass spectrometry (LC-MS/MS) -- Capillary electrophoresis coupled with mass spectrometry (CE-MS) -- Matrix-assisted laser desorption/ionization-time of flight coupled with mass spectrometry (MALDI-TOF/MS) -- Solid-phase chromatography coupled with mass spectrometry (SELDI-MS) -- Differential protein profiling -- Mass spectrometry -- (a) Peptide mass fingerprinting -- (b) Electrospray ionization -- (c) Peptide sequencing using tandem mass spectrometers
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| 650 |
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0 |
|a Kidneys
|x Diseases
|x Molecular diagnosis.
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| 650 |
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|a Biochemical markers.
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| 650 |
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2 |
|a Biomarkers
|0 (DNLM)D015415
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| 650 |
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6 |
|a Reins
|0 (CaQQLa)201-0003219
|x Maladies
|0 (CaQQLa)201-0003219
|x Diagnostic mol�eculaire.
|0 (CaQQLa)201-0382639
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| 650 |
|
6 |
|a Marqueurs biologiques.
|0 (CaQQLa)201-0177920
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| 650 |
|
7 |
|a Biochemical markers
|2 fast
|0 (OCoLC)fst00831950
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| 700 |
1 |
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|a Ahuja, Seema S.
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| 700 |
1 |
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|a Castillo, Brian.
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| 776 |
0 |
8 |
|i Print version:
|z 0128159235
|z 9780128159231
|w (OCoLC)1130246577
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128159231
|z Texto completo
|
