Comprehensive overview of irritable bowel syndrome clinical and basic science /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Fichna, Jakub
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2020.
Temas:
Irritable colon.
Irritable Bowel Syndrome
C�olon irritable.
Irritable colon
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • A Comprehensive Overview of Irritable Bowel Syndrome
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter 1: Introduction to irritable bowel syndrome: General overview and epidemiology
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • References
  • Chapter 2: Pathogenesis of irritable bowel syndrome
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • Fundamentals-Impaired gut motility and visceral hypersensitivity in IBS
  • Alteration in gut motility
  • Visceral hypersensitivity
  • Factors and mechanisms in IBS pathology
  • Brain-gut axis
  • Serotonin and its metabolism
  • Possible role of peptide YY
  • Histamine and mast cells
  • Gut microbiota
  • Genetics
  • Low-grade mucosal inflammation and immune activation
  • The role of diet in IBS
  • Conclusions
  • References
  • Chapter 3: Irritable bowel syndrome and the brain-gut connection
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • Introduction
  • BGA anatomy and IBS
  • Hypothalamic-pituitary-adrenal axis
  • Enteric nervous system
  • Immune system
  • Central nervous system
  • The microbiota-brain-gut axis
  • MBGA pathways
  • 5-HT
  • SCFAs
  • GABA
  • Restoring the microbiota-brain-gut axis to treat IBS
  • Conclusion
  • References
  • Chapter 4: The control of the intestinal epithelium integrity in irritable bowel syndrome patients
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • Mechanical barrier
  • Intestinal microbiota
  • Immunological activation in irritable bowel syndrome
  • T cells
  • Mast cells
  • Macrophages and eosinophils
  • B cells
  • Immune system activation in IBS
  • Nervous system
  • Conclusions
  • Acknowledgments
  • References
  • Chapter 5: Irritable bowel syndrome and gut microbiota
  • Abbreviations
  • Abbreviations
  • Gut microbiota
  • Post-infectious IBS (PI-IBS)
  • Microbiota-brain-gut axis
  • Gut microbiota alteration in IBS
  • Small intestine bacterial overgrowth
  • Prebiotics, probiotics and synbiotics
  • Fecal microbiota transplantation
  • Conclusions
  • Acknowledgments
  • References
  • Chapter 6: Gender-related differences and significance of gonadal hormones in irritable bowel syndrome
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • Gender-related differences in irritable bowel syndrome
  • Gonadal hormones in irritable bowel syndrome
  • Estrogen and androgen receptors in irritable bowel syndrome
  • Gonadal hormones in the colonic motility modulation
  • Gonadal hormones in the visceral pain regulation
  • Conclusions
  • Acknowledgments
  • References
  • Chapter 7: Genetic aspect (with SNPs) of irritable bowel syndrome
  • List of abbreviations
  • List of abbreviations
  • List of abbreviations
  • Introduction
  • Mutations within genes related to voltage-gated sodium channel
  • Single nucleotide polymorphisms associated with IBS pathophysiology
  • Serotonin genes
  • Serotonin transporter gene
  • Serotonin receptor genes

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