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Epigenetics of the immune system /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Kabelitz, Dieter (Editor ), Bhat, Jaydeep (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press, [2020]
Colección:Translational epigenetics series ; v. 16.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Intro
  • Epigenetics of the Immune System
  • Copyright
  • Contents
  • Contributors
  • Preface
  • Chapter 1: An introduction to immunology and epigenetics
  • Development of immune cells
  • Dynamics of the immune response
  • Immunological memory
  • Basic overview of epigenetic regulation
  • Genome architecture at primary structure scale: Cis-regulation through DNA elements
  • Genome architecture at secondary structure scale: Trans-regulation through chromatin packaging and nucleosome positioning
  • Genome architecture at tertiary structure scale: Long-range chromatic interactions and gene regulation within chromatin ter ...
  • Posttranscriptional regulation of RNA expression
  • Posttranslational modifications: Chromatin remodeling complexes and histones
  • Posttranslational modifications: Nonhistone proteins
  • Advancing technology and use of interdisciplinary approaches
  • References
  • Chapter 2: Plant epigenetics and the `intelligent� priming system to combat biotic stress
  • Introduction
  • Plant DNA methylation
  • De novo DNA methylation
  • Maintenance DNA methylation
  • Histone modifications
  • RNA-associated silencing
  • Epigenetics of plant microbe interactions
  • Epigenetics of plant insect interactions
  • Epigenetics of immune system and memory in plants
  • Plant epigenetics: Model plants and application in agriculture
  • Somatic embryogenesis
  • Heterosis
  • Conclusions
  • References
  • Chapter 3: Understanding immune system development: An epigenetic perspective
  • Introduction: An outline of the chapter
  • Epigenetic modifications and their functional output
  • Transcriptional control of epigenetic modifications: From on/off to cycling of epigenetic modifications
  • DNA methylation: The mark of silence
  • Histone modifications: Key epigenetic drivers
  • Interdependence of DNA and histone modifications
  • Epigenetic modifications mediated by chromatin remodeling and noncoding RNA (ncRNA)
  • Accessible chromatin: A prelude to transcription
  • Poised state of a gene: Epigenetic modifications priming gene for activation
  • Epigenetic mechanisms regulating immune cell development
  • Epigenetic regulation during hematopoiesis
  • Development of innate immune cells: Regulation by epigenetic processes
  • Development of natural killer (NK) cells
  • ILC2 cell development
  • Development of macrophages
  • Development of dendritic cells
  • Transcription factors and epigenetic mechanisms involved in DC development
  • Epigenetic mechanisms in adaptive immune system
  • B-cell development and differentiation-An epigenetic perspective
  • Pro-B to pre-B cell commitment
  • Pre-B to immature B cells-Formation of BCR
  • Peripheral differentiation of B cells
  • Role of epigenetic regulation in T cells