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Physiologically based pharmacokinetic (PBPK) modeling : methods and applications in toxicology and risk assessment /

Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, clas...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Fisher, Jeffrey W., Gearhart, Jeffery M., Lin, Zhoumeng
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London ; San Diego, CA : Academic Press, [2020]
Temas:
Acceso en línea:Texto completo
Descripción
Sumario:Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. There are end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments.
Notas:Includes index.
Descripción Física:1 online resource
ISBN:9780128196823
0128196823