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SCIDIR_on1153897989 |
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20231120010449.0 |
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m o d |
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200509s2020 maua o 000 0 eng d |
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|a EBLCP
|b eng
|e rda
|c EBLCP
|d CUS
|d YDX
|d OPELS
|d OCLCF
|d UKMGB
|d GZM
|d CASUM
|d OCLCO
|d KUK
|d OCLCO
|d OCL
|d OCLCQ
|d OCLCO
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|a GBC055162
|2 bnb
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|a 019786244
|2 Uk
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|a 1153069929
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|a 9780128201473
|q (electronic bk.)
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|a 0128201479
|q (electronic bk.)
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|z 9780128201442
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|z 0128201444
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| 035 |
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|a (OCoLC)1153897989
|z (OCoLC)1153069929
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| 050 |
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4 |
|a QP801.R47
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| 082 |
0 |
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|a 572/.58
|2 23
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| 245 |
0 |
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|a Retinoid signaling pathways /
|c edited by Ehmke Pohl.
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press,
|c 2020.
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| 300 |
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|a 1 online resource (xx, 590 pages) :
|b illustrations
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods in enzymology ;
|v v. 637
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| 505 |
0 |
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|a Intro -- Retinoid Signaling Pathways -- Copyright -- Contents -- Contributors -- Preface -- Chapter One: Vitamin A and its natural derivatives -- 1. Vitamin A: Molecules and biochemical properties -- 1.1. Vitamin A brief history and nomenclature -- 1.2. Natural derivatives of retinol -- 1.3. Lipid properties of retinoids -- 1.4. Physiological concentrations of natural retinoids -- 1.5. Retinoid signaling: Delivery of retinol to tissues and cells -- 2. Retinoid signaling in vision -- 3. Retinoid signaling in growth and development -- 4. Future work -- References
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| 505 |
8 |
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|a Chapter Two: Post-natal all-trans-retinoic acid biosynthesis -- 1. Introduction -- 2. ATRA and hormesis -- 3. Retinol dehydrogenases -- 3.1. Background -- 3.2. Functions of mRdh1/hRdh16 -- 3.3. Rdh10 functions -- 3.3.1. Post-natal, non-ocular Rdh10 functions -- 3.3.2. Rdh10 and cancer -- 3.4. Dhrs9 contributions to ATRA biosynthesis -- 3.4.1. Dhrs9 in hair and skin -- 3.4.2. Dhrs9 and tumor progression -- 3.4.2.1. Dhrs9 and immunity -- 3.5. RdhE2 and E2S (retinol dehydrogenases epidermal 2 and 2 similar) -- 3.6. Other Rdh -- 3.7. A cautionary note
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| 505 |
8 |
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|a 4. Retinal reductases (Rrd) and retinoid metabolism -- 4.1. The reductase Dhrs3 (mouse and human retSDR1, hSdr16C1, hRdh17) -- 4.1.1. Dhrs3 and cancer -- 4.2. An uncertain contribution of Rdh13 (Pan2) -- 4.3. The reductase Dhrs4 (mouse Rrd -- human 2,4-dienoyl-CoA reductase) -- 4.4. The reductase Rdh11 (mouse and human RalR1, Psdr1 scald and human Sdr7C1) -- 5. Regulation of ATRA tissue concentrations -- 6. The multiplicity of enzymes in the retinoid metabolon -- 7. Alcohol dehydrogenases -- 8. Retinal dehydrogenases -- 8.1. Raldh and disease -- References
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8 |
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|a 4.5. Chromatography -- 4.6. Kinetic studies -- 4.7. Analysis and statistics -- 4.8. Non-genomic BP functions -- 5. Summary -- References -- Chapter Four: Generation and isolation of recombinant retinoid oxidoreductase complex -- 1. Introduction -- 2. The short-chain dehydrogenase/reductase 16C (SDR16C) family of enzymes -- 3. The retinoid oxidoreductase complex (ROC) -- 4. The baculovirus expression system -- 5. Calcium phosphate precipitation -- 6. Protocol -- 6.1. Equipment -- 6.2. Reagents -- 6.3. Buffer preparation -- 6.3.1. Recombinant baculovirus generation buffers -- 6.3.2. Subcellular fractionation buffers
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8 |
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|a Chapter Three: Retinoid metabolism and functions mediated by retinoid binding-proteins -- 1. Nature of the BP -- 1.1. Crbp2 (encoded by rbp2) -- 1.2. Crbp1 (encoded by rbp1) -- 2. BP contributions to retinoid metabolism -- 2.1. Crbp contributions to retinol and retinal metabolism -- 2.2. Crabp contributions to ATRA catabolism -- 2.3. Fabp5 and ATRA function -- 3. Experimental methods -- 3.1. Definition -- 3.2. Rationale -- 3.3. Materials, equipment and reagents -- 4. Protocols -- 4.1. BP preparation -- 4.2. Retinoid purification -- 4.3. UV analyses -- 4.4. Tissue, cell and homogenate extraction.
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| 588 |
0 |
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|a Print version of record.
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| 650 |
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0 |
|a Retinoids.
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| 650 |
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0 |
|a Cellular signal transduction.
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| 650 |
1 |
2 |
|a Retinoids
|0 (DNLM)D012176
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| 650 |
1 |
2 |
|a Signal Transduction
|0 (DNLM)D015398
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| 650 |
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6 |
|a R�etino�ides.
|0 (CaQQLa)201-0032576
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| 650 |
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6 |
|a Transduction du signal cellulaire.
|0 (CaQQLa)201-0206812
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| 650 |
|
7 |
|a Cellular signal transduction
|2 fast
|0 (OCoLC)fst00850288
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| 650 |
|
7 |
|a Retinoids
|2 fast
|0 (OCoLC)fst01096230
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| 655 |
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4 |
|a Internet Resources.
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| 655 |
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4 |
|a Index not Present.
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| 700 |
1 |
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|a Pohl, Ehmke,
|e editor
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| 776 |
0 |
8 |
|i Print version:
|a Pohl, Ehmke
|t Retinoid Signaling Pathways
|d San Diego : Elsevier Science & Technology,c2020
|z 9780128201442
|
| 830 |
|
0 |
|a Methods in enzymology ;
|v v. 637.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/bookseries/00766879/637
|z Texto completo
|
