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Pathology : oxidative stress and dietary antioxidants /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2020.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover
- Pathology
- Copyright Page
- Contents
- List of contributors
- Preface
- I. Oxidative Stress and Pathology
- 1 Free radicals: what they are and what they do
- List of abbreviations
- Introduction
- Free radicals: general characteristics
- Oxidative chain reactions
- Selected free and nonfree radicals: characteristics and behavior
- Superoxide radical (O2)
- Hydrogen peroxide (H2O2)
- Hydroxyl radical (OH)
- Alkoxyl (RO) and peroxyl (ROO) radicals
- Singlet oxygen (1O2)
- Ozone (O3)
- Hypochlorous acid (HOCl)
- Nitric oxide (nitrogen monoxide
- NO)
- Other reactive nitrogen species
- Sources of free radicals
- Mitochondria
- Peroxisomes
- Endoplasmic reticulum
- Oxidative stress
- Proteins
- Deoxyribonucleic acid
- Ribonucleic acid
- Lipids
- Free radicals in health and disease
- Conclusion
- Applications to other areas of pathology
- Summary points
- Acknowledgment
- References
- 2 Oxidative stress in pathologies of male reproductive disorders
- List of abbreviations
- Introduction
- Redox biology in male reproduction
- Oxidative stress and male factor infertility
- Mechanisms of oxidative stress-induced reproductive dysfunction
- Lipid peroxidation
- DNA integrity
- Mitochondrial dysfunction
- Apoptosis
- Assessment of oxidative stress in the male reproductive system
- Use of antioxidants in male infertility treatment
- Nutritional sources
- Supplementary antioxidants
- Phytonutrients
- Antioxidant paradox and reductive stress
- Applications to other areas of pathology
- Conclusion
- Summary points
- References
- 3 Oxidative stress and diabetic retinopathy
- List of abbreviations
- Introduction
- Molecular mechanisms of diabetic retinopathy
- Oxidative stress and reactive oxygen species
- Nonenzymatic production of reactive oxygen species
- Enzymatic production of reactive oxygen species
- Relationship between oxidative stress and other biochemical pathways
- Enhanced polyol pathway
- Increased accumulation of advanced glycation end products
- Activation of protein kinase C
- Activation of hexosamine pathway
- Oxidative stress and structural and functional alterations in diabetic retinopathy
- Basement membrane thickening
- Alterations in retinal microvasculature