Advances and avenues in the development of novel carriers for bioactives /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Singh, Manju Rawat
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, 2020.
Temas:
Drug carriers (Pharmacy)
Biomedical materials.
Drug Carriers
Vecteurs de m�edicaments.
Biomat�eriaux.
Biomedical materials
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Advances and Avenues in the Development of Novel Carriers for Bioactives and Biological Agents
  • Copyright Page
  • Contents
  • List of Contributors
  • 1 Challenges and need of delivery carriers for bioactives and biological agents: an introduction
  • 1.1 Introduction
  • 1.2 Bioactives and biological agents
  • 1.2.1 Phytoactives
  • 1.2.2 Bioactive peptides
  • 1.2.3 Bioactive lipids
  • 1.2.4 Micronutrients
  • 1.3 Therapeutic significance of bioactives
  • 1.4 Need and challenges of delivery carriers for bioactives
  • 1.4.1 Challenges in phytoactive delivery
  • 1.4.2 Challenges in protein and peptides delivery
  • 1.4.2.1 Chemical modification
  • 1.4.2.2 Delivery system
  • 1.4.3 Challenges in vitamins delivery
  • 1.5 Application of nanotechnology for the delivery of bioactives
  • 1.5.1 Nanodelivery carriers for phytoactives or phytomedicines
  • 1.5.1.1 Liposomes
  • 1.5.1.1.1 Anticancer phytoactives
  • 1.5.1.1.2 Antimicrobial phytomedicines
  • 1.5.1.2 Niosomes
  • 1.5.1.2.1 Antitumor phytoactive
  • 1.5.1.2.2 Antiinflammatory phytoactive
  • 1.5.1.3 Solid lipid nanoparticles
  • 1.5.1.4 Polymeric nanoparticles
  • 1.5.1.5 Metal-based nanoparticles
  • 1.5.2 Nanodelivery carrier for bioactive peptides/protein
  • 1.5.2.1 Vaccines delivery
  • 1.5.2.2 Hormone delivery: insulin
  • 1.5.2.3 Enzyme delivery: digestive enzymes
  • 1.5.2.4 Antimicrobial delivery
  • 1.6 Toxicity and safety concern
  • 1.7 Conclusion
  • Declaration of interest
  • References
  • 2 Natural product-based nanomedicine: polymeric nanoparticles as delivery cargoes of food bioactives and nutraceuticals for ...
  • 2.1 Problems with anticancer treatment
  • 2.1.1 Tumor size
  • 2.1.2 Toxicity
  • 2.1.3 Hair loss
  • 2.1.4 Nausea and vomiting
  • 2.1.5 Leukopenia
  • 2.1.6 Mucositis
  • 2.1.7 Drug resistance
  • 2.1.8 Tumor stem cells
  • 2.2 Overcoming drug resistance
  • 2.3 Bioactive molecules found in functional foods and nutraceuticals: antitumor activity and chemotherapy treatment improvement
  • 2.3.1 Caffeine
  • 2.3.2 Catechins
  • 2.3.3 Theobromine
  • 2.3.4 Capsaicin
  • 2.3.5 Sulforaphane
  • 2.3.6 Apigenin
  • 2.3.7 Resveratrol
  • 2.4 Nanotechnology: an alternative way to improve natural products antitumor capacity through better molecules delivery
  • 2.5 Physiological barriers: challenges for natural products target delivery
  • 2.6 Polymeric nanoparticles: use in the oncological area for the delivery of bioactive molecules
  • References
  • Further reading
  • 3 The promising expedition of the delivery systems for monoclonal antibodies
  • 3.1 Introduction
  • 3.2 Monoclonal antibodies
  • 3.2.1 Origins/types of monoclonal antibodies
  • 3.2.2 Production methodologies
  • 3.2.3 Functions and therapeutic applications of monoclonal antibodies
  • 3.2.4 Checkpoints blockade monoclonal antibodies
  • 3.3 Classic delivery systems for monoclonal antibodies

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