Cargando…
Functional foods in cancer prevention and therapy /
Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2020.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Intro
- Functional Foods in Cancer Prevention and Therapy
- Copyright
- Contents
- Contributors
- Author biographies
- Chapter 1: Natural remedies and functional foods as angiogenesis modulators
- Angiogenesis definition and background
- Molecular mechanism of angiogenesis
- Screening methods of angiogenesis modulators
- Natural angiogenesis modulators
- Concluding remarks and future perspective
- References
- Chapter 2: Targeted cancer therapy with bioactive foods and their products
- Introduction
- Pathophysiology of cancer
- Classification of anticancer bioactive foods
- Classification of anticancer bioactive foods based on origin
- Anticancer bioactive foods of plant origin
- Anticancer bioactive foods of animal origin
- Anticancer bioactive foods of microbial origin
- Classification of anticancer bioactive foods based on the mechanism of action
- Antimetastatic bioactive foods
- Antiproliferative bioactive foods
- Bioactive foods inducing apoptosis
- Antiangiogenic bioactive foods
- Anticancer bioactive foods scavenging free radicals
- Anticancer bioactive foods inhibiting matrix metalloproteinases
- Anticancer bioactive foods inducing DNA methylation
- Classification based on the chemical nature of anticancer bioactive food components
- Anticancer bioactive foods with phenolic components
- Anticancer bioactive foods with flavonoid components
- Anticancer bioactive foods with carotenoid components
- Anticancer bioactive foods with saponin components
- Anticancer bioactive foods with fatty acid components
- Anticancer bioactive foods with sulforaphane components
- Anticancer bioactive foods with dietary fiber components
- Conclusion
- References
- Chapter 3: Natural compounds and anticancer effects: The whole is greater than the sum of its parts
- Cancer research
- Anticancer products from nature.
- Main natural cancer therapeutics
- Tubulin-binding agents
- Topoisomerase inhibitors
- Other drugs from natural sources
- Cancer prevention or natural chemopreventive agents
- An example of synergistic interaction
- Conclusion
- References
- Chapter 4: Relationship between functional food and tumor metabolism
- Introduction: Functional foods
- Functional foods exert their beneficial effects mostly through cellular metabolism
- Metabolic dysregulation in tumor cells
- Tumor metabolism: Glycolysis and acidosis
- Tumor metabolism: Mitochondria and altered TCA cycle fate
- Functional foods: Metabolic reprogramming in tumor cells and emerging concepts in therapeutic strategies
- Conclusion
- References
- Chapter 5: Adiponectin-enhancing dietary constituents in cancer prevention
- Introduction
- Inflammation in carcinogenesis
- Antiinflammatory adiponectin and allied compounds
- Omega-3 PUFAs and adiponectin
- Conclusion
- References
- Chapter 6: Lentils (Lens culinaris L.): A candidate chemopreventive and antitumor functional food
- Introduction
- Anticancer chemical constituents of lentils
- High polar phytochemicals
- Polyphenols
- Proteins and bioactive peptides
- Lectins
- Defensin
- Protease inhibitors
- Phytosterols
- Saponins
- Medium polar phytochemicals
- Flavonoids
- Less polar phytochemicals
- Squalene
- Insoluble lentils products
- Fibers
- Phytic acid (hexaphosphorylated inositol, IP6)
- Epidemiological evidence on the chemopreventive potential of lentils
- Experimental evidence
- In vivo studies
- In vitro studies
- Remarks and conclusions
- References
- Chapter 7: Evidence for anticancer properties of honey with emphasis on mechanistic overview
- Introduction
- Chemistry of honey
- Pharmacological uses of honey
- Honey stimulates the immune system
- Honey as antioxidants.
- Bitter gourd (Momordica charantia)
- Future research needed
- References
- Further reading
- Chapter 11: Antioxidant phytochemicals in cancer prevention and therapy-An update
- Introduction
- Cancer: Public health burden and ACM
- Cancer and oxidative stress
- Antioxidant phytochemicals (APH)
- APH in cancer prevention
- APH in cancer therapy
- Metabolic fate of APH
- APHs as prooxidants
- Conclusion
- Acknowledgments
- References
- Further reading
- Chapter 12: Prooxidant anticancer activity of plant-derived polyphenolic compounds: An underappreciated phenomenon
- Introduction
- Cancer chemoprevention and polyphenols
- A copper-mediated prooxidant anticancer mechanism of polyphenols
- Oxidative DNA breakage induced by polyphenols in the presence of copper ions in vitro
- Polyphenols mobilize nuclear copper to mediate prooxidant DNA damage
- Inducing high copper levels in lymphocytes leads to increase in polyphenol-induced DNA breakage
- Polyphenol induced cell death in cancer cells occur through mobilization of intracellular copper and generation of ROS
- Copper-mediated prooxidant anticancer action of polyphenols is augmented at acidic pH microenvironment associated with tumors
- Making sense of the prooxidant action of polyphenols
- Conclusion
- References
- Chapter 13: Plant-based products in cancer prevention and treatment
- Introduction
- Cancer and oxidative stress
- Antioxidant therapeutics in cancer
- Phytochemicals as anticancer therapeutics
- Cellular mechanism of actions of phytochemicals
- Nutraceuticals as anticancer therapy
- Therapeutic efficacy and purification of anticancer phytochemicals
- Development and use of synthetic analogs to plant-derived substances
- Conclusion
- References
- Further reading
- Chapter 14: Overview of probiotics in cancer prevention and therapy
- Introduction.