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200225s2020 enk ob 001 0 eng d |
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|z 9780128181409
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|a (OCoLC)1141665829
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|a Genome engineering via CRISPR-Cas9 system /
|c edited by Vijai Singh, Pawan K. Dhar.
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|a London :
|b Academic Press,
|c [2020]
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|c �2020
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|a 1 online resource
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|a text
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|a Includes bibliographical references and indexes.
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|a An introduction to genome editing CRISPR-Cas systems -- Evolution and molelcular mechanism of CRISPR/Cas9 systems -- Exploring the potential of CRISPR-Cas9 for the removal of human viruses -- Programmable removal of bacterial pathogens using CRISPR-Cas9 system -- Targeted genome editing using CRISPR-Cas9 system in fungi -- CRISPR-Cas9 system for fungi genome engineering toward industrial applications -- Development and challenges of using CRISPR-Cas9 system in mammalians -- CRISPR-Cas9 system "a mighty player in cancer therapy" -- CRISPR-Cas9 for therapy: the challenges and ways to overcome them -- Engineering of Cas9 for improved functionality -- The current progress of CRISPR/Cas9 development in plants -- Fruit crops improvement using CRISPR/Cas9 system -- CRISPR/Cas9 engineered viral immunity in plants -- Genome engineering in medicinally important plants using CRISPR/Cas9 tool -- Genome editing of algal species by CRISPR Cas9 biofuels -- Development and use of CRISPR in industrial applications -- Functional understanding of CRISPR interference: its advantages and limitations for gene silencing in bacteria -- Genome engineering in insects: focus on the CRISPR/Cas9 system -- Recent progress of CRISPR-Cas9 in zebra fish -- CRISPR: a revolutionary tool for genome engineering in the protozoan parasites -- Emergent challenges for CRISPR: biosafety, patenting, and regulatory issues.
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|a Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more.
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|a Genetic engineering.
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|a CRISPR-associated protein 9.
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|a CRISPR-Associated Protein 9
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|a Prot�eine-9 associ�ee �a CRISPR.
|0 (CaQQLa)000311707
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|a CRISPR-associated protein 9.
|2 fast
|0 (OCoLC)fst02000537
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|a Genetic engineering.
|2 fast
|0 (OCoLC)fst00940027
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700 |
1 |
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|a Singh, Vijai,
|e editor.
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700 |
1 |
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|a Dhar, Pawan K.,
|e editor.
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776 |
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8 |
|i Print version:
|z 9780128181416
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776 |
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8 |
|i Print version:
|z 0128181400
|z 9780128181409
|w (OCoLC)1109766225
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128181409
|z Texto completo
|