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Nanomaterials for clinical applications : case studies in nanomedicines /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Pippa, Natassa, Demetzos, Costas
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Elsevier, 2020.
Colección:Micro & nano technologies.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Nanomaterials for Clinical Applications
  • Copyright Page
  • Contents
  • List of contributors
  • 1. Solid lipid nanoparticles in dermaceuticals
  • 1.1 General introduction
  • 1.2 Why solid lipid nanoparticles?
  • 1.2.1 Formulation aspects
  • 1.2.2 Physiological aspects
  • 1.3 Evolution of lipidic nanoparticles from solid lipid nanoparticles to nanostructured lipid carriers
  • 1.4 Cosmetic and topical applications of solid lipid nanoparticles
  • 1.5 Skin penetration with solid lipid nanoparticles
  • 1.6 Mechanism of drug penetration with solid lipid nanoparticles
  • 1.7 Incorporation into semisolid vehicle
  • 1.8 Case studies of successful topical delivery with lipidic nanoparticles
  • 1.8.1 Delivery of antimicrobials
  • 1.9 Delivery of agents for other skin diseases
  • 1.9.1 Solid lipid nanoparticles for cosmetic applications
  • 1.10 Conclusions
  • References
  • 2. Cyclodextrin-based drug delivery systems
  • 2.1 Cyclodextrins-structure, physiochemical properties, and toxicological profile
  • 2.2 Cyclodextrin inclusion complexes-formation, stability, and application in drug delivery
  • 2.3 Cyclodextrin-based products in clinical practice
  • 2.3.3.1 Cyclodextrins in control of obesity and hyperlipidemia
  • References
  • 3. Lipid vesicles for (trans)dermal administration
  • 3.1 (Trans)dermal drug-delivery systems
  • 3.1.1 Human skin barrier to xenobiotics
  • 3.2 Lipid vesicles for breaching the skin barrier
  • 3.2.1 Conventional liposomes
  • 3.2.2 Transfersomes
  • 3.2.3 Ethanol-based lipid vesicles
  • 3.2.3.1 Ethosomes
  • 3.2.3.2 Transethosomes
  • 3.2.3.3 Other lipid vesicles
  • 3.3 Liposomal formulation in clinics
  • 3.3.1 Conventional liposomes
  • 3.3.2 Transfersomes
  • 3.3.3 Ethosomes
  • 3.4 Final remarks
  • References
  • 4. Stimuli-responsive nanocarriers for drug delivery
  • 4.1 Introduction
  • 4.2 Types of stimuli
  • 4.2.1 pH-responsive nanosystems
  • 4.2.2 Thermoresponsive nanosystems
  • 4.3 Development of chimeric stimuli-responsive liposomes with incorporated stimuli-responsive polymers
  • 4.3.1 pH-responsive liposomes
  • 4.3.2 Thermoresponsive liposomes
  • 4.4 Thermotropic behavior of stimuli-responsive liposomes
  • 4.4.1 Thermal analysis on pH-responsive liposomes
  • 4.4.2 Thermal analysis of thermoresponsive liposomes
  • 4.5 Physicochemical properties of stimuli-responsive liposomes