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|a 1135412524
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|a 0128220279
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|a 9780128220276
|q (electronic bk.)
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|z 9780128194942
|q (print)
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|z 0128194944
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|a (OCoLC)1135667936
|z (OCoLC)1135412524
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|a RC269
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|a 616.99/407
|2 23
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|a Tumor vascularization /
|c edited by Domenico Ribatti and Francesco Pezzella.
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| 260 |
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|a London :
|b Academic Press,
|c 2020.
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| 300 |
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|a 1 online resource (200 pages)
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Print version record.
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|a Front Cover -- Tumor Vascularization -- Copyright Page -- Contents -- List of contributors -- Preface -- 1 Sprouting and nonsprouting angiogenesis in tumors -- Introduction -- The angiogenic switch -- Sprouting tumor angiogenesis -- Intussusceptive microvascular growth angiogenesis -- Glomeruloid vascular proliferation -- Concluding remarks -- References -- 2 Nonangiogenic tumor growth -- Introduction -- Identification of nonangiogenic tumors -- Alveolar growth pattern -- Lepidic growth pattern -- Interstitial growth pattern -- Perivascular (cuffing) growth pattern
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| 505 |
8 |
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|a The biology of nonangiogenic growth -- Hypoxia and angiogenesis -- Inflammation and immune response -- Motility, invasion, and cell-cell adhesion -- Energy metabolism -- What causes tumors to grow in an angiogenic or nonangiogenic, vessel co-opting way? -- Blood vessels change when they are co-opted by malignant cells -- Conclusion -- References -- 3 Vascular co-option -- Vascular co-option in normal and transformed cells -- Vascular co-option in non-cancer cells -- Vascular co-option in cancer cells -- Molecular regulation of vascular co-option
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| 505 |
8 |
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|a Molecular regulation of cell adhesion and proliferation in vascular co-option -- Molecular regulation of migration and invasion linked to vascular co-option -- Molecular regulation of dormancy, latency, and awakening linked to vascular co-option -- Preclinical applications to target vascular co-option: prevention of metastasis -- Acknowledgments -- References -- 4 Pericyte mimicry: an embryogenesis-derived program of extravascular tumor cell migration -- Introduction -- Interactions between tumor cells and blood vessels -- History -- Angiotropism, PM and EVMM -- PM in melanoma -- Histopathology
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| 505 |
8 |
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|a Histological criteria -- Melanoma liver metastases -- Experimental models of PM -- Prognostic significance of angiotropism and PM -- Molecular findings -- Angiotropism, PM, and EVMM in non-melanoma tumors -- Molecular studies -- Laminin and cancer cell migration -- Laminins in melanoma -- Laminins in non-melanoma tumors -- Modulation of laminins in embryogenesis and in cancer progression -- PM and EVMM: Reversion to an embryogenesis-derived program -- Analogies between embryogenesis and cancer development -- Neural crest cell migration: a model for PM/EVMM -- Angiogenesis -- Cell competition
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| 505 |
8 |
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|a PM and EVMM: routes, direction and timing according to an embryogenesis-derived program -- Space, direction, and timing -- Perspectives and therapeutic implications -- Detection of PM and EVMM -- Therapeutic perspectives -- DAN -- YAP signaling -- Laminins -- Concluding remarks -- PM and vascular co-option: complementary embryonic phenomena? -- Acknowledgments -- References -- 5 Vasculogenic mimicry -- Introduction -- Vasculogenic mimicry in prognosis and progress -- Molecular pathway of vasculogenic mimicry -- Hypoxia/hypoxia-inducible factor pathway -- Vascular endothelial-cadherin pathway
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| 500 |
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|a Long noncoding RNAs pathway
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| 500 |
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|a Includes index.
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| 650 |
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0 |
|a Tumors
|x Blood-vessels.
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| 650 |
1 |
2 |
|a Neoplasms
|x blood.
|0 https://id.nlm.nih.gov/mesh/D009369Q000097
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| 650 |
2 |
2 |
|a Blood Vessels.
|0 https://id.nlm.nih.gov/mesh/D001808
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| 650 |
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6 |
|a Tumeurs
|x Vaisseaux sanguins.
|0 (CaQQLa)201-0108151
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| 650 |
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7 |
|a Tumors
|x Blood-vessels.
|2 fast
|0 (OCoLC)fst01158762
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| 700 |
1 |
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|a Ribatti, Domenico,
|d 1956-
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| 700 |
1 |
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|a Pezzella, Francesco.
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| 776 |
0 |
8 |
|i Print version:
|a Ribatti, Domenico.
|t Tumor Vascularization.
|d San Diego : Elsevier Science & Technology, �2020
|z 9780128194942
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| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128194942
|z Texto completo
|
