Small Molecule Drug Discovery : Methods, Molecules and Applications /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Trabocchi, Andrea (Editor ), Lenci, Elena (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2020]
Temas:
Drug development.
Bioactive compounds.
M�edicaments > D�eveloppement.
Compos�es bioactifs.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • 1 Synthetic approaches toward small molecule libraries
  • 2 Chemical reactions for building small molecules
  • 3 Chemoinformatics approaches to assess chemical diversity and complexity of small molecules
  • 4 Virtual screening of small-molecule libraries
  • 5 Screening and biophysics in small molecule discovery
  • 6 Principles and applications of small molecule peptidomimetics
  • 7 sp2-Iminosugars as chemical mimics for glycodrug design
  • 8 Synthesis and biological properties of spiroacetal-containing small molecules
  • 9 Centrocountins--synthesis and chemical biology of nature inspired indoloquinolizines
  • 10 PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors
  • 11 Discovery of small molecules for the treatment of Alzheimer's disease

Ejemplares similares