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191104s2019 ne o 000 0 eng d |
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|a 0128173297
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|a 9780128173299
|q (electronic bk.)
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|z 9780128169209
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|z 0128169206
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|a (OCoLC)1126285689
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|a RD651
|b .B54 2019
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|a 616.994
|2 23
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|a Bignold, Leon P.,
|d 1947-
|e author.
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1 |
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|a Principles of tumors :
|b a translational approach to foundations /
|c Leon P. Bignold.
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250 |
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|a Second edition.
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264 |
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1 |
|a Amsterdam :
|b Academic Press,
|c 2019.
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300 |
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|a 1 online resource
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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500 |
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|a Previous edition: 2015.
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|a Print version record.
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|a "[This book] provides a concise summary of translational/interdisciplinary topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morphological abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology. This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine."--Website ebook
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|a 1 -- Introduction -- 2 -- Theories and definitions of tumors -- 3 -- Etiopathogenesis of tumors -- 4 -- Growth of cells, growth factors, and oncogenes -- 5 -- Hereditary predispositions to tumors, tumor suppressor genes, and their clinico-genomic complexities -- 6 -- The tumor types: The complexities in the combinations and variabilities of their traits -- 7 -- Epidemiology of tumors -- 8 -- Prevention of tumors -- 9 -- Clinical features of tumors -- 10 -- Typing, grading, and staging of cases of tumor -- 11 -- Endoscopic visualization and imaging assessments of cases of tumor -- 12 -- Principles of surgery for tumors -- 13 -- Principles of nonsurgical therapies -- 14 -- Aspects of radiation therapy -- 15 -- Specific aspects of cytotoxic and hormonal drug therapies -- 16 -- Immunotherapies -- 17 -- Gene therapies not related to immunological therapies -- 18 -- Less common and controversial therapies -- 19 -- Care after primary therapy -- 20 -- Costs, ethics, and malpractice litigation -- Appendix 1 -- Principles of normal embryology, histology, and related cell biology -- Appendix 2 -- Aspects of the normal genome -- Appendix 3 -- Fixed genomic events and possible mechanisms of their causation by etiological agents -- Appendix 4 -- Genomic instabilities: kind, effects, and roles in the immortality of tumor cell populations -- Appendix 5 -- Methods in histologic and molecular assessments of tumors -- Appendix 6 -- "Biomarkers" in molecular pathology and oncology -- Appendix 7 -- Sublethal injuries and deaths of cells and tissues -- Appendix 8 -- "Pretarget," "target," and recovery capacity defenses of cells against carcinogens and cytotoxic agents -- Appendix 9 -- Developing and testing new therapies: clinical trials
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|a Tumors.
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650 |
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|a Neoplasms
|0 (DNLM)D009369
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|a Tumeurs.
|0 (CaQQLa)201-0079779
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650 |
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7 |
|a Tumors
|2 fast
|0 (OCoLC)fst01158759
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776 |
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8 |
|i Print version:
|z 9780128169209
|w (OCoLC)1124241174
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128169209
|z Texto completo
|