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Translational medicine in CNS drug development /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
[2019]
|
| Edición: | First edition. |
| Colección: | Handbook of behavioral neuroscience ;
v. 29. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Translating animal models of obesity and diabetes to the clinic / B.M. Geiger and E.N. Pothos
- Giomarker-guided drug development for better defined early patient studies and clinical trial efficiency / Aldemar Degroot
- Modeling and simulation in the translational pharmacology of CNS drugs / Elizabeth C. De Lange and Peter Bonate
- Functional measurements of central nervous system drug effects in early human drug development / Joop van Gerven
- Experimental medicine approaches in CNS drug development / Jeffrey Paul
- New approaches in translational medicine for Phase I clinical trials of CNS drugs / Matthew Macaluso, Michael Krams, Jonathan Savitz, Wayne C. Drevets, and Sheldon H. Preskorn
- Translational approaches for antidepressant drug development / Gerard J. Marek
- Biomarker opportunities to enrich clinical trial populations for drug development in schizophrenia and depression / Bruce J. Kinon
- PET occupancy and competition in translational medicine and CNS drug development / Paul Cumming and Gerhard Gr|nder
- Stable isotope labeling kinetics in CNS translational medicine : introduction to SILK technology / Randall J. Bateman ... [et. al.]
- Applications of neurophysiological biomarkers in CNS drug development : focus on psychoses / Yash B. Joshi, Melissa A. Tarasenko, and Gregory A. Light
- Heart rate variability as a translational biomarker for emotional and cognitive deficits / Bart A. Ellenbroek, Meyrick Kidwell, Joyce Colussi-Mas, and Jiun Youn
- Drug discovery in psychiatry : time for human genome-guided solutions / Andreas Papassotiropoulos and Dominique J.-F. de Quervain
- Use of cognition to guide decisions about the safety and efficacy of drugs in early-phase clinical trials / Paul Maruff
- Digital biomarkers in clinical drug development / Amir Kalali, Sarah Richerson, Emilia Ouzunova, Ryan Westphal, and Bradley Miller
- Lessons learned from public private partnerships and consortia : the ADNI paradigm / Enchi Liu
- Regulatory perspectives on the use of biomarkers and personalized medicine in CNS drug development : the FDA viewpoint / Mathangi Gopalakrishnan and Jogarao V.S. Gobburu
- Regulatory considerations for the use of biomarkers and personalized medicine in CNS drug development : a European perspective / Eamon O'Loinsigh and Anjana Bose
- Regulatory science objectives and biomarker qualification through public-private partnerships are critical to delivering innovative treatments for CNS diseases / Diane T. Stephenson and Stephen P. Arneri
- The assessment of cognition in translational medicine : a contrast between the approaches used in Alzheimer's disease and major depressive disorder / John E. Harrison and Suzanne Hendrix
- Translational medicine strategies in drug development for neurodevelopmental disorders / Siddharth Srivastava, Mustafa Sahin, and Lisa Prock
- Translational medicine strategies in drug development for mood disorders / Zihang Pan, Radu C. Grovu, and Roger S. McIntyre
- Translational medicine strategies in Alzheimer's disease drug development / Veronika Logovinsky
- Experimental medicine models in generalized anxiety disorder and social anxiety disorder / David S. Baldwin and Ayman Abou-Aisha
- Translational medicine strategies in PTSD drug development / Dan J. Stein, Willie Daniels, and Brian H. Harvey
- Translating neurobiology into practice in tobacco, alcohol, drug, and behavioral addictions / Benjamin Srivastava and Mark S. Gold
- Translational medicine strategies for drug development for impulsive aggression / Emil F. Coccaro, Royce Lee, and Neal G. Simon
- Hypothesizing major depression as a subset of remard deficiency syndrome (RDS) linked to polymorphic reward genes ; considerations for translational medicine approaches for future drug development
- Traveling through the storm : leveraging virtual patient monitoring and artificial intelligence to observe, predict, and affect patient behavior in CNS drug development / Adam Hanina and Laura Shafner.