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|a 1229507269
|a 1235837465
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|a 9780128139400
|q (electronic bk.)
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|a 0128139404
|q (electronic bk.)
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|a 0128139390
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|a 9780128139394
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|z 9780128139394
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|a (OCoLC)1103918307
|z (OCoLC)1229507269
|z (OCoLC)1235837465
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|a RM301.3.G45
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|a 2019 G-375
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|a MED
|x 071000
|2 bisacsh
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0 |
4 |
|a 615.7
|2 23
|
| 100 |
1 |
|
|a Cacabelos, R.
|q (Ram�on),
|d 1955-
|e author.
|
| 245 |
1 |
0 |
|a Pharmacoepigenetics /
|c Ram�on Cacabelos.
|
| 250 |
|
|
|a First edition.
|
| 264 |
|
1 |
|a London :
|b Academic Press, an imprint of Elsevier,
|c [2019]
|
| 264 |
|
4 |
|c �2019
|
| 300 |
|
|
|a 1 online resource
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Translational epigenetics series ;
|v volume 10
|
| 505 |
0 |
|
|a Front Cover; Pharmacoepigenetics; Copyright; Contents; Contributors; Pharmacoepigenetics: A Long Way Ahead; Chapter 1: The Epigenetic Machinery in the Life Cycle and Pharmacoepigenetics; 1.1. Introduction; 1.2. The Epigenetic Machinery; 1.2.1. DNA Methylation; 1.2.2. DNA Demethylation; 1.2.2.1. Ten-Eleven Translocation (TET) Proteins; 1.2.2.2. AID/APOBEC Family Cytidine Deaminases; 1.2.2.3. BER (Base Excision Repair) Glycosylases; 1.2.3. Chromatin Remodeling and Histone Modifications; 1.2.3.1. Chromatin; 1.2.3.1.1. Genome-Wide Chromatin Conformation, Spatial Organization, and 3D Genomics
|
| 505 |
8 |
|
|a 1.2.3.2. Histones1.2.3.3. Posttranslational Modifications; 1.2.3.3.1. Histone Methylation-Demethylation; 1.2.3.3.2. Histone Acetylation; 1.2.3.3.3. Histone Deacetylation; Sirtuins; 1.2.3.3.4. Histone Acylation; 1.2.3.3.5. Histone Propionylation; 1.2.3.3.6. N-Glycosylation and O-GlcNAcylation; 1.2.3.3.7. Ubiquitination-Deubiquitination; 1.2.3.3.8. SUMOylation; 1.2.3.3.9. Histone Phosphorylation-Dephosphorylation; 1.2.3.3.10. Histone Chaperonization; 1.2.3.3.11. Glutathionylation; 1.2.3.3.12. Poly ADP-Ribosylation; 1.2.3.3.13. Oxidative Stress; 1.2.3.4. Other Posttranslational Changes
|
| 505 |
8 |
|
|a 1.2.3.5. Noncoding RNAs1.2.3.5.1. miRNAs; 1.2.3.5.2. circRNAs; 1.2.3.5.3. RNA Methylation; 1.2.3.6. Other Operational Elements of the Epigenetic Machinery; 1.2.3.6.1. DNA Replication Regulators; 1.2.3.6.2. N6-Adenine DNA Methylation; 1.2.3.6.3. Transcription Factors; 1.2.3.6.4. Transcriptional Repression; 1.2.3.6.5. Polycomb Group Proteins: Polycomb Repressive Complex 2 (PRC2); 1.2.3.6.6. BET (Bromodomain and Extraterminal Domain) Proteins; 1.2.3.6.7. UHRF1; 1.2.3.6.8. Plant Homeodomain (PHD) Fingers; 1.2.3.6.9. HDACs; 1.2.3.6.10. Chromatin-Remodeling Factors
|
| 505 |
8 |
|
|a 1.2.3.6.11. Heterochromatin and Gene Silencing1.2.3.6.12. MEN1; 1.2.3.6.13. NPC, HOXA, and Nup93; 1.2.3.6.14. CCR4; 1.2.3.6.15. HP1; 1.2.3.6.16. TORC1; 1.2.3.6.17. WDR5; 1.2.3.6.18. Nudt21; 1.2.3.6.19. Trithorax-Group Proteins; 1.2.3.6.20. SUUR Protein; 1.2.3.6.21. Kap123; 1.2.3.6.22. SET Complex; 1.2.3.6.23. Histone Code Reader Spin1; 1.2.3.6.24. Proteasome; 1.2.3.6.25. Lipid Mediators; 1.2.3.6.26. Transposable Elements; 1.2.3.6.27. Intragenic Enhancers; 1.2.3.6.28. Genomic Regulatory Regions; 1.3. Singular Epigenetic Phenomena; 1.3.1. Aneuploidy; 1.3.2. X Chromosome Inactivation
|
| 505 |
8 |
|
|a 1.3.3. Meiotic Silencing1.3.4. RNA Splicing; 1.3.5. Copy Number Variation (CNV); 1.3.6. The Epigenetic Clock; 1.3.7. Epigenetic Reprogramming Memory; 1.3.8. Transgenerational Epigenetic Inheritance; 1.3.9. DNA Repair Pathways and Genomic Instability; 1.3.10. Antibody Maturation; 1.3.11. Sexual Dimorphism; 1.3.12. Heritable RNAi; 1.3.13. Genomic Imprinting; 1.4. Evolution; 1.5. Population Epigenetics; 1.6. Fertility and Gestation; 1.6.1. In Vitro Fertilization and Assisted Reproduction Technology; 1.7. Placenta; 1.8. Lactation; 1.9. Development; 1.10. Maturation, Aging, and Longevity
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 588 |
0 |
|
|a Online resource; title from PDF title page (EBSCO, viewed June 10, 2019).
|
| 650 |
|
0 |
|a Pharmacogenetics.
|
| 650 |
|
0 |
|a Pharmacogenomics.
|
| 650 |
|
0 |
|a Epigenetics.
|
| 650 |
1 |
2 |
|a Pharmacogenetics
|0 (DNLM)D010597
|
| 650 |
2 |
2 |
|a Epigenomics
|0 (DNLM)D057890
|
| 650 |
2 |
2 |
|a Epigenesis, Genetic
|0 (DNLM)D044127
|
| 650 |
|
6 |
|a Pharmacog�en�etique.
|0 (CaQQLa)201-0042441
|
| 650 |
|
6 |
|a Pharmacog�enomique.
|0 (CaQQLa)201-0322837
|
| 650 |
|
6 |
|a �Epig�en�etique.
|0 (CaQQLa)000270630
|
| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
| 650 |
|
7 |
|a Epigenetics
|2 fast
|0 (OCoLC)fst01893642
|
| 650 |
|
7 |
|a Pharmacogenetics
|2 fast
|0 (OCoLC)fst01060243
|
| 650 |
|
7 |
|a Pharmacogenomics
|2 fast
|0 (OCoLC)fst01060245
|
| 655 |
|
4 |
|a Internet Resources.
|
| 830 |
|
0 |
|a Translational epigenetics series ;
|v v. 10.
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128139394
|z Texto completo
|
