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|a 9780128148792
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|z 9780128148792
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|a (OCoLC)1102638945
|z (OCoLC)1229737389
|z (OCoLC)1235825207
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|a 572.865
|2 23
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|a Palacios, Daniela,
|e author.
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|a Epigenetics and regeneration /
|c Daniela Palacios.
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250 |
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|a First edition.
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264 |
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|a London :
|b Academic Press,
|c 2019.
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264 |
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|c �2019
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300 |
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|a 1 online resource
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Translational epigenetics series ;
|v v. 11
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500 |
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|a Includes index.
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|a Includes bibliographical references and index.
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|a Online resource; title from PDF title page (EBSCO, viewed June 3, 2019).
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|a Front Cover; Epigenetics and Regeneration; Copyright; Contents; Contributors; Chapter 1: Epigenetics and Regeneration: An Overview; 1.1. Introduction; 1.2. Epigenetic Regulation of Gene Expression and Cell Fate; 1.3. Development, Reprogramming, and Tissue Regeneration: From the Zygote to Emerging Sources of Multipotent Cells for Re ... ; 1.4. The Epigenetics of Tissue Development, Homeostasis, and Regeneration; 1.5. Epigenetics and Environment: How Age, Environmental Cues, and Epigenetic Drugs Influence The Capability of Stem Cell ...
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|a 1.6. Conclusions: Is There a Place for Epigenetics in Regenerative Medicine?Acknowledgments; List of Abbreviations; References; Section I: Epigenetics: Molecular Players and Mechanisms; Chapter 2: Dynamics and Mechanisms of DNA Methylation Reprogramming; 2.1. Introduction; 2.2. DNA Methylation Machinery; 2.3. DNA Demethylation; 2.4. DNA Methylation in Early Development; 2.5. How Necessary is DNA Methylation Reprogramming for Early Development?; 2.6. DNA Methylation Trajectories During Reprogramming of Somatic Cells; 2.7. 6-Methyldeoxyadenosine in Mammalian DNA?; 2.8. Future Perspectives
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|a AcknowledgmentsReferences; Chapter 3: Histone Modifications; 3.1. Epigenetics and Chromatin Dynamics; 3.2. Histone Modifications; 3.2.1. Histone Lysine Acetylation; 3.2.2. Histone Lysine Methylation; 3.2.3. Histone Lysine Methylation in Transcription; 3.2.3.1. Gene silencing by histone H3 lysine 9 and lysine 27 methylation; 3.2.3.2. Gene activation by H3 lysine 4 and H3 lysine 36 methylation; 3.2.4. Histone Arginine Methylation; 3.2.5. Histone Phosphorylation; 3.2.6. Histone Ubiquitination; 3.2.7. Histone Sumoylation; 3.2.8. Histone Glycosylation; 3.2.9. Histone Poly-ADP Ribosylation
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|a 3.3. The Histone Code3.3.1. Bivalent Domains, Promoters, and Enhancers; 3.3.2. Histone Modifications and Nuclear Organization; 3.4. Histone Modifications in Cell Fate Changes and Cell Differentiation; 3.4.1. Histone Modifications as Regulators of Neuronal Development and Function; 3.4.2. Histone Mutations in Disease: The Example of Histone Gene Mutations in Brain Tumors; 3.4.3. Histone Modifications in Skeletal Muscle Differentiation and Regeneration; 3.5. Conclusions and Perspectives; List of Abbreviations; References
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|a Chapter 4: Noncoding RNAs as Regulators of Gene Expression in Pluripotency and Differentiation4.1. Introduction; 4.1.1. Classification and Mechanisms of Action; 4.2. The Role of miRNAs in Pluripotency; 4.2.1. miRNAs as Regulators of the Cell Cycle and Apoptosis of Embryonic Stem Cells (ESCs); 4.2.2. miRNAs Regulating the Maintenance of Self-Renewal and Pluripotency of ESCs; 4.2.3. miRNAs in Somatic Cell Reprogramming Towards iPSCs; 4.3. miRNAs as Regulators of Cell Fate and Cell Differentiation; 4.3.1. miRNAs and Regulation of Muscle Differentiation
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650 |
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|a Epigenetics.
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650 |
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0 |
|a Regeneration (Biology)
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650 |
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2 |
|a Epigenomics
|0 (DNLM)D057890
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650 |
|
2 |
|a Regeneration
|0 (DNLM)D012038
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650 |
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6 |
|a �Epig�en�etique.
|0 (CaQQLa)000270630
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650 |
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6 |
|a R�eg�en�eration (Biologie)
|0 (CaQQLa)201-0015702
|
650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Biochemistry.
|2 bisacsh
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650 |
|
7 |
|a Epigenetics
|2 fast
|0 (OCoLC)fst01893642
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650 |
|
7 |
|a Regeneration (Biology)
|2 fast
|0 (OCoLC)fst01093042
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655 |
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4 |
|a Internet Resources.
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830 |
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|a Translational epigenetics series ;
|v v. 11.
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856 |
4 |
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|u https://sciencedirect.uam.elogim.com/science/book/9780128148792
|z Texto completo
|