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190415s2019 ne a ob 001 0 eng d |
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|a 019308783
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|a 1097254662
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|a 1100577499
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|a 9780128166284
|q (electronic book)
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|a 0128166282
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|z 0128165049
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|z 9780128165041
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|a (OCoLC)1097184260
|z (OCoLC)1097254662
|z (OCoLC)1097975131
|z (OCoLC)1100577499
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|a RM262
|b .N36 2019
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|a MED
|x 071000
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|a 615.5/8
|2 23
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|a Nanoparticles in pharmacotherapy /
|c edited by Alexandru Mihai Grumezescu.
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|a Amsterdam, Netherlands ;
|a Oxford, United Kingdom ;
|a Cambridge, MA, United States :
|b Elsevier,
|c [2019]
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300 |
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|a 1 online resource (xxvii, 603 pages :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
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|a Micro and nano technologies series
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|a Includes bibliographical references and index.
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|a Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, medical doctors and those in academia.
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|a Print version record.
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|a Front Cover; Nanoparticles in Pharmacotherapy; Copyright Page; Contents; List of Contributors; Foreword; Preface; 1 Pharmacotherapy and nanotechnology; 1.1 Introduction; 1.2 Carriers for Antiinfective Therapy; 1.3 Carriers for Antiinflammatory Therapy; 1.4 Carriers for Anticancer Therapy; 1.5 Conclusions; References; 2 Nanostructures in pharma: elixir to oral medicine; 2.1 Nanocrystals; 2.1.1 Mechanism of Nanocrystals Improved Performance and Properties; 2.1.1.1 Surface area; 2.1.1.2 Apparent solubility and supersaturation; 2.1.1.3 Amorphous state of the nanocrystals
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|a 2.1.2 Manufacturing of Nanocrystals2.1.3 Bottom-Up Techniques; 2.1.3.1 Nanoprecipitation; 2.1.3.2 Supercritical fluid processing; 2.1.3.3 Spray drying; 2.1.3.4 Freeze drying; 2.1.3.5 Others; 2.1.4 Top-Down Techniques; 2.1.4.1 Nanomilling/media milling; 2.1.4.2 High pressure homogenization; 2.1.5 General Issues: Cause, Effect, and Solution; 2.1.5.1 Crystal growth and agglomeration; 2.1.5.2 Polymorphism; 2.1.6 Characterization of Nanocrystals; 2.1.6.1 Particle size analysis; 2.1.6.2 Physical testing; 2.1.6.3 Morphology; 2.1.6.4 Dispersion testing; 2.1.6.5 Chemical analysis
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|a 2.2 Polymeric Nanoparticles2.2.1 In Vivo Evaluation of Oral Nanoparticles; 2.2.1.1 Types of in vivo evaluation tests; 2.2.1.2 Pharmacokinetic studies; 2.2.1.3 Drug efficacy studies; 2.2.1.4 Drug transport and distribution studies; 2.2.1.5 Histopathological examination studies; 2.2.2 Characterization of the Nanoparticles by Various Techniques; 2.2.2.1 Particle size and distribution; 2.2.2.1.1 Photon-correlation spectroscopy; 2.2.2.1.2 Scanning electron microscopy; 2.2.2.1.3 Transmission electron microscopy; 2.2.2.1.4 Cryo-transmission electron microscopy; 2.2.2.1.5 Atomic force microscopy
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|a 2.2.2.2 Molecular weight2.2.2.2.1 Gel chromatography; 2.2.2.3 Surface charge; 2.2.2.3.1 Zeta potential measurement; 2.2.2.3.2 Laser Doppler anemometry; 2.2.2.4 Hydrophobicity; 2.2.2.5 Surface element analysis; 2.2.2.5.1 X-ray photon spectroscopy; 2.2.2.5.2 Nuclear magnetic resonance; 2.2.3 Nanoparticles-brain delivery; 2.3 Future Directions and Conclusions; References; 3 Polymeric micelles in biomedical science; 3.1 Introduction; 3.2 Preparation of Polymeric Micelles; 3.2.1 Synthetic Strategies for Polymeric Micelles; 3.2.1.1 Conventional approach; 3.2.1.2 Polyion complex micelles
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|a 3.2.1.3 Noncovalent approach3.3 Preparation of Drug-Loaded Polymeric Micelles; 3.3.1 Direct Dissolution Method; 3.3.2 Solvent Evaporation; 3.3.3 Dialysis; 3.3.4 Lyophilization Method; 3.4 Characterization of Polymeric Micelles; 3.4.1 Critical Micelle Concentration; 3.4.2 Size and Shape of Polymeric Micelles; 3.4.3 Electrophoretic Measurements; 3.4.4 Nuclear Magnetic Resonance; 3.4.5 Differential Scanning Calorimetry; 3.4.6 Flow Cytometry Analysis; 3.4.7 Stability of Polymeric Micelles; 3.5 Application of Polymeric Micelles in Biomedical Sciences; 3.5.1 Passive Drug Targeting
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650 |
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|a Chemotherapy.
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650 |
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0 |
|a Nanoparticles.
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650 |
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2 |
|a Nanoparticles
|x therapeutic use
|0 (DNLM)D053758Q000627
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650 |
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2 |
|a Drug Therapy
|0 (DNLM)D004358
|
650 |
|
2 |
|a Nanoparticles
|0 (DNLM)D053758
|
650 |
|
6 |
|a Chimioth�erapie.
|0 (CaQQLa)201-0034750
|
650 |
|
6 |
|a Nanoparticules.
|0 (CaQQLa)201-0262530
|
650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
650 |
|
7 |
|a Chemotherapy.
|2 fast
|0 (OCoLC)fst00853595
|
650 |
|
7 |
|a Nanoparticles.
|2 fast
|0 (OCoLC)fst01032624
|
700 |
1 |
|
|a Grumezescu, Alexandru Mihai,
|e editor.
|
776 |
0 |
8 |
|i Print version:
|a GRUMEZESCU, ALEXANDRU MIHAI.
|t NANOPARTICLES IN PHARMACOTHERAPY.
|d [Place of publication not identified] : WILLIAM ANDREW PUBLISHING, 2019
|z 0128165049
|w (OCoLC)1078719188
|
830 |
|
0 |
|a Micro & nano technologies.
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128165041
|z Texto completo
|