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Quorum sensing : molecular mechanism and biotechnological application /
Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease,...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
[Place of publication not identified] :
Academic Press,
2019.
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| Edición: | First edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Quorum Sensing: Molecular Mechanism and Biotechnological Application; Copyright; Dedication; Contents; Contributors; Preface; Part 1: General: Chemistry and Microbiology; Chapter 1: The Chemical Language of Gram-Negative Bacteria; 1. Introduction; 2. Quorum Sensing System Architectures in Gram-Negative Bacteria; 2.1. AHL-Based Quorum Sensing; 2.2. AI-2 Based Quorum Sensing; 2.3. QS Systems Using Other Autoinducers; 3. Chemistry of Autoinducers; 3.1. N-Acyl Homoserine Lactones; 3.2. Cyclic Furanone Compounds; 3.3. Others; 3.4. Quorum Sensing in Marine Environments
- 4. Quorum Quenching Molecules4.1. A Case Study of Inhibitors of AHL Receptors: LasR Antagonists; 4.2. Enzymatic Inhibition of QS; 4.2.1. Enzymatic degradation and inactivation of AHLs; 4.2.2. Enzymatic degradation and inactivation of non-AHLs quorum sensing signals; 4.2.3. Biosynthesis inhibition of AHLs molecules; 4.2.4. Biosynthesis inhibition of AI-2; 5. Conclusion; Glossary; Abbreviations; References; Chapter 2: Analytical Approaches for the Identification of Quorum Sensing Molecules; 1. Introduction; 2. Sample Preparation; 2.1. Liquid-Liquid Extraction (LLE)
- 2.2. Solid Phase Extraction (SPE)3. Detection, Identification, and Quantification of QS Molecules; 3.1. Analytical Approaches for AHL Detection; 3.1.1. Biosensors; 3.1.2. Radiolabeled assays; 3.1.3. Colorimetric assays; 3.2. Analytical Approaches for AHL Identification and Quantification; 3.2.1. Gas chromatography-mass spectrometry (GC-MS); 3.2.2. Liquid chromatography-mass spectrometry (LC-MS); 3.2.3. Capillary electrophoresis-mass spectrometry (CE-MS); 3.2.4. Matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS); 3.2.5. Nuclear magnetic resonance spectroscopy
- 3.3. Analytical Approaches for Identification and Quantification of Other QS Molecules4. Concluding Remarks; Glossary; Abbreviations; References; Chapter 3: Quorum Sensing in Marine Biofilms and Environments; 1. Introduction; 2. The Discovery of and Growing Interest in Quorum Sensing in Marine Environments; 2.1. 1970s: Quorum Sensing was Discovered in the Marine Environment-The Vibrio-squid Model; 2.2. 1990-2010s: A Growing Interest in the Study of Quorum Sensing in Marine Environments
- 3. Overview of Prokaryotic Diversity and Compounds Involved in Quorum Sensing in Marine Environments and Biofilms3.1. Experimental Approaches to Characterize AIs in the Marine Environment; 3.2. AHLs, or Autoinducer-1 (AI-1); 3.3. Autoinducer-2 (AI-2); 3.4. Other AIs; 3.5. Diffusion of AIs in the Marine Environment; 3.6. V. harveyi (and the Harveyi clade), a Model for the Study of Quorum Sensing in Marine Bacteria; 4. Surface Biofilms and Holobionts: The Diversity of Microbial Habitats Enabling Quorum Sensing in the Marine Environment