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|a Vertebrate skeletal development /
|c edited by Bjorn R. Olsen.
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|a First edition.
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|a Cambridge, MA :
|b Academic Press, an imprint of Elsevier,
|c [2019]
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|c �2019
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|a 1 online resource
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|a text
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|a Current topics in developmental biology ;
|v volume one hundred and thirty three
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|a Includes bibliographical references.
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|a Vendor-supplied metadata.
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|a Front Cover; Vertebrate Skeletal Development; Copyright; Contents; Contributors; Preface; Chapter One: Stem and progenitor cells in skeletal development; 1. Introduction; 2. Colony-forming unit fibroblasts (CFU-Fs) and mesenchymal/skeletal stem cells (MSCs/SSCs): A traditional definition for ... ; 3. How relevant are CFU-Fs and MSCs/SSCs to skeletal development?; 4. In vivo lineage-tracing experiments in mice: An unambiguous approach to reveal cell fates; 5. Endochondral bone development/Phase 1: Formation of the growth plate
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|a 6. Endochondral bone development/Phase 2: Formation of the perichondrium and osteoblast precursors7. Endochondral bone development/Phase 3: Formation of the primary ossification center and the bone marrow cavity; 8. Endochondral bone development/Phase 4: Formation of the postnatal growth plate and continued growth of the marrow space; 9. Endochondral bone development/Phase 5: Establishment and maintenance of the adult bone marrow stroma; 10. Periosteum and craniofacial sutures; 11. Sox9 osteoblast precursors; 12. Parathyroid hormone (PTH) action on skeletal precursors
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|a 5.3. Discoidin domain receptors6. Conclusions and implications; Acknowledgments; References; Chapter Three: Development of the axial skeleton and intervertebral disc; 1. Introduction; 2. Development of somite derived structures; 2.1. Somitogenesis; 2.2. Sclerotome specification; 2.3. Resegmentation; 2.4. Sclerotome derivatives; 2.4.1. Vertebra; 2.4.2. Annulus fibrosus; 2.4.3. Tendon/ligament; 3. Development of the nucleus pulposus from notochord; 3.1. Formation and function of the notochord; 3.1.1. Notochord sheath; 3.2. Identification of notochordal and NP markers
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|a 3.3. Notochord-to-nucleus pulposus transition3.4. Maintenance of the nucleus pulposus; 4. Conclusions and implications; Acknowledgments; References; Chapter Four: Regulatory mechanisms of jaw bone and tooth development; 1. An overview of jaw bone and tooth development; 2. Early development of the first pharyngeal arch; 2.1. Cellular contributions to mandible and maxilla development; 2.2. Molecular identity of the developing mandible and maxilla; 3. Jaw bone development; 3.1. Meckel�s cartilage; 3.2. Mandibular bone osteogenesis; 3.3. Hemifacial microsomia
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|a Vertebrates
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|a Vertebrates.
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|a Bone Development
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|a SCIENCE
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|a Olsen, Bj�rn Reino,
|e editor.
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|i Print version:
|t Vertebrate skeletal development.
|b First edition.
|d Cambridge, MA : Academic Press, an imprint of Elsevier, [2019]
|z 0128104872
|z 9780128104873
|w (OCoLC)1051681317
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|a Current topics in developmental biology ;
|v v. 133.
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|z Texto completo
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|a 13. Wnt/β-catenin signaling and cell fate decision14. Conclusions and perspectives; Acknowledgments; References; Chapter Two: ECM signaling in cartilage development and endochondral ossification; 1. Introduction; 2. Chondrogenesis and endochondral ossification; 3. Roles of integrins in chondrogenesis and further chondrocyte maturation; 4. Integrin downstream partners: Connecting ECM to the cell cytoskeleton; 4.1. Focal adhesion kinase; 4.2. Rho GTPases: Family members with different functions; 4.3. MAP kinase cascade; 5. Other non-integrin cell receptors; 5.1. CD44; 5.2. Syndecan
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