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1 |
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|a Montgomery, Erwin B.,
|c Jr.,
|e author.
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1 |
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|a Reproducibility in biomedical research :
|b epistemological and statistical problems /
|c Erwin B. Montgomery, Jr.
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| 264 |
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1 |
|a London, United Kingdom :
|b Academic Press, an imprint of Elsevier,
|c 2019.
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| 300 |
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|a 1 online resource
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| 336 |
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|a text
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|a Includes bibliographical references and index.
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0 |
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|a Online resource; title from PDF title page (ScienceDirect, viewed March 19, 2019).
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|a Front Cover; Reproducibility in Biomedical Research; Copyright Page; Dedication; Quote; Contents; Preface; Prologue; 1 Introduction; Science as Argumentation Within the Experiment and Within the Community; Scientific Argumentation and Logic; The Multifaceted Notion of Irreproducibility; Productive Irreproducibility; Ontology Versus Epistemology; The Use of Logical Formalism; Summary; 2 The Problem of Irreproducibility; Type I and II Errors; Controlling the Inevitability of Irreproducibility Risk; Institutional Responses; Reproducibility and Irreproducibility
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| 505 |
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|a Contributions of Logic to Biomedical ResearchReductionism and Conceptual (Broad) Irreproducibility; Variability, Central Tendency, Chaos, and Complexity; Conceptual Reproducibility and the Importance of Hypothesis Generation; Summary; 3 Validity of Biomedical Science, Reproducibility, and Irreproducibility; Science Must Be Doing Something Right and Therein Lies Reproducibility and Productive Irreproducibility; Science Versus Human Knowledge of It; The Necessity of Enabling Assumptions; The Centrality of Reproducibility; The Central Tendency; The Scientific Method; Reductionism; Causality
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| 505 |
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|a Special Cases of Irreproducible ReproducibilityScience as Inference to the Best Explanation; Summary; 4 The Logic of Certainty Versus the Logic of Discovery; Certainty, Reproducibility, and Logic; Deductive Logic-Certainty and Limitations; Syllogistic Deduction; Judicious Use of the Fallacy of Four Terms; Partial, Probability, Practical, and Causal Syllogisms; Propositional Logic; Induction; The Duhem-Quine Thesis; Summary; 5 The Logic of Probability and Statistics; The Value of the Logical Perspective in Probability and Statistics
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| 505 |
8 |
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|a Metaphysics: Ontology Versus Epistemology and Biomedical ReproducibilityIndependence of Probabilities and Regression Toward the Mean; Avoiding the Fallacy of Four Terms; The Conflation of Ontology and Epistemology; Summary; 6 Causation, Process Metaphor, and Reductionism; Practical Syllogism and Beyond; Centrality of Hypothesis to Experimentation and Centrality of Causation to Hypothesis Generation; Reductionism and the Fallacies of Composition and Division; Other Fallacies as Applied to Cause; Discipline in the Principle of Causational and Informational Synonymy; Summary
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| 505 |
8 |
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|a 7 Case Studies in Clinical Biomedical ResearchForbearance of Repetition; Setting the Stage; Clinical Meaningfulness; Statistics and Internal Validity; Establishing Clinical Meaningfulness; Specific Features to Look for in Case Studies; Case Study-Two Conflicting Studies of Hormone Use in Postmenopausal Women, Which Is Irreproducible?; Summary; 8 Case Studies in Basic Biomedical Research; Forbearance of Repetition; Purpose; Setting the Stage; The Value of a Tool from Its Intended Use; What is Basic Biomedical Research?; Scientific Meaning Versus Statistical Significance
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|a Biology
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|i Print version:
|a Montgomery, Erwin B., Jr.
|t Reproducibility in biomedical research.
|d London, United Kingdom : Academic Press, an imprint of Elsevier, 2019
|z 0128174439
|z 9780128174432
|w (OCoLC)1048933746
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128174432
|z Texto completo
|
