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Platelets /

"Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Michelson, Alan D. (Editor ), Cattaneo, M. (Editor ), Frelinger, Andrew L. (Editor ), Newman, Peter J. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press, an imprint of Elsevier, 2019.
Edición:Fourth edition.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Platelets; Copyright; Contents; Contributors; Preface; Foreword: A Brief History of Ideas About Platelets in Health and Disease; The Role of Platelets in Human Hemostasis, Platelet Transfusion, and Bleeding Time; Immune Thrombocytopenia; Alloantigens, Single Nucleotide Polymorphisms, and Alloimmune Thrombocytopenias; Platelet Physiology, Assays of Platelet ``Adhesiveness,�� ADP, Platelet Aggregation, Myocardial Infarction, and P2Y12 Antag ... ; Aspirin, Arachidonic Acid, Prostaglandins, Eicosanoids, Nitric Oxide, Endothelial Ecto-ADPase (CD39), Angiogenesis, Micropa ...
  • A Comparison of Human Platelets and Limulus AmebocytesThe Evolution of Hemostasis and Blood Coagulation; Megakaryocytes and Mammals; Marine Mammals; Order Monotremata; Order Marsupialia; Platelet Levels; A Comparison of Nonplacental and Placental Mammals; Conclusions; References; Chapter 2: Megakaryocyte Development and Platelet Formation; Introduction; Megakaryocyte Development; The Hematopoietic Program; Committed Megakaryocyte Progenitor Cells; Immediate Megakaryocyte Precursors; Endomitosis and Polyploid Formation; Megakaryocyte Cytoplasmic Maturation; Invaginated Membrane System
  • Dense Tubular SystemGranules; Platelet Formation; Mechanisms of Platelet Production; Budding From the Megakaryocyte Surface; Cytoplasmic Fragmentation via the Invaginated Membrane System; Proplatelet Formation; The Proplatelet Theory; Proplatelet Morphogenesis; The Cytoskeletal Mechanics of Proplatelet Formation; Microtubules Power Proplatelet Elongation; Actin-Dependent Proplatelet Branching; Organelle Transport in Proplatelets; Spectrin-Based Membrane Skeleton in Platelet Production; Release of Platelets; The Sites of Platelet Formation In Vivo; Platelet Formation in the Bone Marrow