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SCIDIR_on1088558283 |
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|a 019270552
|2 Uk
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|a 1090859115
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|a 9780128132609
|q (electronic bk.)
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|a 0128132604
|q (electronic bk.)
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|z 9780128132593
|q (print)
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|z 0128132590
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|z (OCoLC)1090859115
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|a 612.7/51
|2 23
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| 245 |
0 |
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|a Basic and applied bone biology /
|c edited by David B. Burr, Matthew R. Allen.
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| 250 |
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|a Second edition.
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| 264 |
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1 |
|a London, United Kingdom :
|b Academic Press, an imprint of Elsevier,
|c [2019]
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| 264 |
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4 |
|c �2019
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| 300 |
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|a 1 online resource (xvii, 460 pages) :
|b illustrations (some color)
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| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references and index.
|
| 588 |
0 |
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|a Online resource; title from PDF title page (ScienceDirect, viewed February 27, 2019).
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| 505 |
0 |
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|a Front Cover -- BASIC AND APPLIED BONE BIOLOGY -- BASIC AND APPLIED BONE BIOLOGY -- Copyright -- Dedication -- Contents -- List of Contributors -- Biographies -- Preface (First Edition) -- Preface (Second Edition) -- I -- BASIC BONE BIOLOGY AND PHYSIOLOGY -- 1 -- Bone Morphology and Organization -- THE FUNCTIONS OF BONE -- BONE IS ORGANIZED AS A MULTISCALE MATERIAL -- BONE COMPOSITION -- THE NANOSCALE ORGANIZATION OF BONE -- Collagen -- Enzymatically Mediated Collagen Cross-Linking -- Nonenzymatically Mediated Collagen Cross-Linking -- Collagen Orientation -- Bone Mineral
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| 505 |
8 |
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|a Noncollagenous Extracellular Matrix Proteins -- Proteoglycans and Glycosaminoglycans -- Glycoproteins -- SIBLING Proteins -- Osteocalcin -- Osteonectin -- THE MICROSTRUCTURAL ORGANIZATION OF BONE -- Woven Bone -- Primary Bone -- Primary Lamellar Bone -- Plexiform Bone -- Primary Osteons -- Secondary Bone -- Interstitial Bone -- THE MACROSCOPIC ORGANIZATION OF BONE -- Cortical Bone -- Skeletal Envelopes -- THE BLOOD SUPPLY AND INNERVATION OF BONE -- Blood Supply -- Innervation of Bone -- BONE FLUID COMPARTMENTS -- BONE MASS AND BONE QUALITY -- Rate of Bone Turnover -- Bone Trabecular Architecture
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| 505 |
8 |
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|a Tissue Material (Intrinsic) Properties -- Microdamage Accumulation -- Suggested Readings -- 2 -- Bone Marrow and the Stem Cell Niche -- NICHES IN DEVELOPMENT -- IMAGING OF NICHES -- BONE MARROW NICHE CELLS -- Nonhematopoietic -- Osteoblastic Cells -- Mesenchymal Stromal/Stem Cell Populations -- Adipocytes -- Endothelial Cells -- Hematopoietic -- Megakaryocytes -- Macrophages -- Neutrophils -- Osteoclasts -- NEURONAL REGULATION OF THE HEMATOPOIETIC STEM CELL NICHE -- HORMONAL REGULATION OF THE HEMATOPOIETIC STEM CELL NICHE -- NICHES AND MALIGNANCIES -- AGING AND THE BONE MARROW MICROENVIRONMENT
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| 505 |
8 |
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|a THE FUTURE -- Suggested Readings -- 3 -- Bone Cells -- OSTEOCLASTS -- Osteoclast Morphology and Function -- Osteoclast Differentiation and Fusion -- Osteoclast Apoptosis -- Regulation of Osteoclast Generation and Survival -- OSTEOBLASTS -- Osteoblast Morphology and Function -- Osteoblast Formation and Differentiation -- Osteoblast Apoptosis -- Regulation of Osteoblast Generation and Survival -- Bone Lining Cells -- OSTEOCYTES -- Osteocyte Morphology and Functions -- Osteocytogenesis and Osteocyte Maturation -- Osteocyte Apoptosis: Consequences and Regulation
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| 505 |
8 |
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|a Preservation of Osteocyte Viability by Mechanical Stimuli -- Aging and Osteocyte Apoptosis -- Hormonal Regulation of Osteocyte Life Span -- Regulation of Bone Formation by Osteocytes: The Sclerostin Paradigm -- Regulation of Bone Resorption by Osteocytes: RANKL and OPG -- Regulation of Bone Mineralization by Osteocytes -- Suggested Readings -- 4 -- Local Regulation of Bone Cell Function -- OVERVIEW OF CYTOKINES AND GROWTH FACTORS AND THEIR RECEPTORS -- Definition: Cytokines Versus Growth Factors -- Soluble Ligands -- Membrane-Bound Ligands -- Receptor Classification -- Signal Transduction Cascades
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| 650 |
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0 |
|a Bones.
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| 650 |
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2 |
|a Bone and Bones
|0 (DNLM)D001842
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| 650 |
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6 |
|a Os.
|0 (CaQQLa)201-0070794
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| 650 |
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7 |
|a bonnets (hats)
|2 aat
|0 (CStmoGRI)aat300210720
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| 650 |
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|a Bones.
|2 fast
|0 (OCoLC)fst00835991
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| 655 |
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0 |
|a Electronic books.
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| 700 |
1 |
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|a Burr, David B.,
|e editor.
|
| 700 |
1 |
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|a Allen, Matthew R.
|c (Professor of anatomy and cell biology),
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Basic and applied bone biology.
|b Second edition.
|d London : Elsevier/Academic Press, [2019]
|z 9780128132593
|w (OCoLC)1047776335
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128132593
|z Texto completo
|
