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Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders /
Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a var...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom :
Academic Press, an imprint of Elsevier,
[2019]
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Morbidelli, Lucia, |e author. | |
| 245 | 1 | 0 | |a Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders / |c Lucia Morbidelli, Benjamin Bonavida. |
| 264 | 1 | |a London, United Kingdom : |b Academic Press, an imprint of Elsevier, |c [2019] | |
| 264 | 4 | |c �2019 | |
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | |a Online resource; title from PDF title page (EBSCO, viewed February 13, 2019). | ||
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn's disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. | ||
| 505 | 0 | |a Front Cover; Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders; Copyright; Contents; Contributors; About the Editors and Acknowledgements; Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders; Preface; Part 1: Applications of Nitric Oxide in Cancer; Chapter 1: Nitric Oxide-Releasing Engineered Nanoparticles: Tools for Overcoming Drug Resistance in Chemotherapy; Conflict of Interest; Introduction: Overview of Nitric Oxide in Cancer Biology; Nanotechnology in Cancer: The Enhanced Permeability and Retention Effect Allied to NO Donors | |
| 505 | 8 | |a Combination of NO-Releasing Nanomaterials and Conventional Anticancer ChemotherapiesSelected Examples of NO-Releasing Nanomaterials for Cancer Treatment; Conclusions: Perspectives and Challenges; Acknowledgments; References; Chapter 2: Reversal of Multiple Cancer Oncogenic Pleiotropic Properties by NO-Modulating Therapies; Conflict of Interest; Introduction; Antineoplastic Activities of NO in Cancer Cells and the Underlying Molecular Mechanisms; NO and Tumor Initiation, Growth, and Apoptosis; NO and Tumor Metastasis; NO and Tumor Cell Stemness | |
| 505 | 8 | |a NO and Tumor Resistance to Conventional Chemotherapy and Immune-Mediated CytotoxicityAntineoplastic Activities of NO in Tumor Milieu and the Underlying Molecular Mechanisms; NO and Tumor Angiogenesis; NO and Immunoediting of Immune Signals by the Tumor Microenvironment; Nitric Oxide Novel Applications in Cancer Treatment and Prevention; NO Donors; NO Donor Conjugates; NO-Releasing Nanoparticles; NOS Gene Targeting; Conclusions; Acknowledgment; References; Chapter 3: Antitumor Effect of a Metal-Nonoate Through Angiogenesis Impairment; Conflict of Interest; Introduction; Results; Conclusions | |
| 505 | 8 | |a AcknowledgmentsReferences; Chapter 4: Therapeutic Implications of the Nitric Oxide Pathway in the Angiogenesis of Tumors and Inflammatory-Related Di ... ; Conflict of Interest; Angiogenesis: Definition and Pathophysiological Roles; Regulation of Endogenous NO Production and Vascular Physiology; Role of NO in Angiogenesis; How NO Controls Angiogenesis; Direct Effects of NO on Endothelial Cells; NO as a Mediator of the Angiogenic Factor Activity; NOS Inhibition as Effector of Antiangiogenic Molecules and Antitumor Drugs | |
| 505 | 8 | |a NO Controls the Angiogenic Modulator Expression or Activity in Endothelial, Tumor, and Stromal CellsContadictory Roles of NO in Tumor Angiogenesis; Innovative Strategies for Controlled NO Availability; Conclusions; Acknowledgments; References; Chapter 5: Nitric Oxide and Cancer: To Inhibit or To Induce iNOS: That Is the Question?; Conflict of Interest; NO: Its Generation and Signaling; NO and Cancer; iNOS Inhibition Strategies; iNOS Induction Strategies; Does Exposure to NO Cause Human Cancer?; The Tumor Microenvironment: iNOS, Innate Immunity, and Cancer; Final Thoughts and Future Directions | |
| 650 | 0 | |a Nitric oxide |x Physiological effect. | |
| 650 | 0 | |a Nitric oxide |x Pathophysiology. | |
| 650 | 0 | |a Nitric oxide |x Therapeutic use. | |
| 650 | 0 | |a Cancer |x Treatment. | |
| 650 | 0 | |a Inflammation |x Treatment. | |
| 650 | 2 | |a Neoplasms |x therapy |0 (DNLM)D009369Q000628 | |
| 650 | 2 | |a Nitric Oxide |x therapeutic use |0 (DNLM)D009569Q000627 | |
| 650 | 6 | |a Cancer |x Traitement. |0 (CaQQLa)201-0004693 | |
| 650 | 6 | |a Inflammation (Pathologie) |0 (CaQQLa)201-0026988 |x Traitement. |0 (CaQQLa)201-0377521 | |
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| 650 | 7 | |a SCIENCE |x Life Sciences |x Human Anatomy & Physiology. |2 bisacsh | |
| 650 | 7 | |a Cancer |x Treatment. |2 fast |0 (OCoLC)fst00845538 | |
| 650 | 7 | |a Nitric oxide |x Pathophysiology. |2 fast |0 (OCoLC)fst01037989 | |
| 650 | 7 | |a Nitric oxide |x Physiological effect. |2 fast |0 (OCoLC)fst01037990 | |
| 700 | 1 | |a Bonavida, Benjamin, |e author. | |
| 776 | 0 | 8 | |i Print version: |a Morbidelli, Lucia. |t Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders. |d London, United Kingdom : Academic Press, an imprint of Elsevier, [2019] |z 0128165456 |z 9780128165454 |w (OCoLC)1044816675 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128165454 |z Texto completo |