Cargando…
Advances in ion mobility-mass spectrometry : fundamentals, instrumentation and applications /
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier,
2019.
|
| Colección: | Comprehensive analystical chemistry ;
volume 83 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Ion Mobility-Mass Spectrometry: Fundamentals, Instrumentation and Applications; Copyright; Contents; Contributors to Volume 83; Series Editor�s Preface; Preface; Chapter One: Modelling Collisional Cross Sections; 1. Introduction; 2. Projection Approximation; 3. Projected Superposition Approximation and Local Collision Probability Approximation; 4. Exact Hard-Spheres Scattering; 5. Trajectory Method; 6. Conclusions and Outlook; References; Chapter Two: Tandem Mobility Spectrometry at Ambient Pressure; 1. Introduction; 2. Tandem DMS/IMS2; 2.1. Description of DMS/IMS2
- 2.2. Modes of Operation2.3. Summary and Final Thoughts on DMS/IMS2; 3. Tandem FAIMS-IMS (MS); 4. Reactive Stages for Tandem Mobility Spectrometry; 4.1. Transformations of Gas Ions at Ambient Pressure; 4.2. Fragmentation in DMS Analysers; 4.3. Fragmentation in IMS Analysers; 5. Tandem Differential Mobility Spectrometry; 5.1. DMS/DMS in Purified Air Atmosphere; 5.2. Reactive Stages in Tandem DMS; 5.2.1. Reagent Vapour Clustering Between Stages; 5.2.2. Fragmentation of Ions in Tandem DMS; 5.3. Summary of Tandem DMS; 6. Tandem Ion Mobility Spectrometry at Ambient Pressure
- 6.1. Kinetic IMS and Tandem Drift Tubes6.2. IMS With Reactive Stages; 6.2.1. Electric Field Fragmentation of Mobility-Selected Ions of Explosives; 6.2.2. Ion Fragmentation of Mobility-Selected Positive Ions; 6.2.3. Summary and Analysis; 6.3. Tandem Differential Mobility Analysers; References; Chapter Three: Ion-Mobility Mass Spectrometry for Chiral Analysis of Small Molecules; 1. Introduction; 2. Mass Spectrometry for Chiral Discrimination; 2.1. Relative Abundances of Host-Guest Complexes; 2.2. Ion-Molecule Reactions; 2.3. Kinetic Method; 3. Ion-Mobility Spectrometry for Chiral Discrimination
- 3.1. The Use of Chiral Modifier Gas3.2. The Use of a Chiral Selector and Metal Ions; 3.3. Metal Ion Free Chiral Recognition; 4. Conclusions; References; Chapter Four: Dynamic Clustering and Ion Microsolvation; 1. Introduction; 2. The Effect of the Asymmetric Field; 2.1. Differential Mobility in a Hard Sphere Environment (Type C Behaviour); 2.2. Introduction of Solvent Vapour (Type A and Type B Behaviour); 2.3. Exotic Dispersion Curves (Type D and Type E Behaviour); 3. Using DMS Clustering Behaviour to Assess Molecular Properties
- 3.1. Correlating Type B Critical Points With Molecular Properties3.2. Application of Supervised ML; Acknowledgements; References; Chapter Five: Ion Mobility-Mass Spectrometry in Metabolomic, Lipidomic, and Proteomic Analyses; 1. Introduction; 2. Ion Mobility-Mass Spectrometry in Metabolomics and Lipidomics; 2.1. Identification and Quantitation of Metabolites; 2.2. Lipidomics: A Structurally Challenging Class of Molecules; 3. Ion Mobility-Mass Spectrometry in Proteomics; 3.1. Bottom-up Proteomics Approaches; 3.2. The Role of IMS-MS in Structural Proteomics