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Erythropoietin /
Erythropoietin, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions a...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Cambridge, MA :
Academic Press, is an imprint of Elsevier,
2017.
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| Colección: | Vitamins and hormones ;
v. 105. |
| Temas: | |
| Acceso en línea: | Texto completo |
| Sumario: | Erythropoietin, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. Each thoroughly reviewed volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors and others. Erythropoietin is a kidney cytokine-like hormone that is responsible for maintaining the homeostasis of oxygen in the circulation. In case of hypoxia or anemia, erythropoietin acts through a complex regulatory system involving the hypoxia-inducible factor and hypoxia-response elements in the genome to cause red blood cells to proliferate and differentiate. Although this system has been understood to account for the main activity of erythropoietin, it is currently known that erythropoietin has many other additional physiological activities. This volume documents the activities of this vital molecule and also describes the structure and function of erythropoietin and its receptor as well as newly designed small-molecule agonists. |
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| Notas: | <Ol><li><b>Erythropoietin Receptor Structural Domains<br></b><i>Qingxin Li and CongBao Kang</i></li><li><b>Analysis of the Asymmetry of Activated EPO Receptor Enables Designing Small Molecule Agonists<br></b><i>Frank Guarnieri</i></li><li><b>Endogenous Erythropoietin<br></b><i>Steven J. Korzeniewski and Athina Pappas</i></li><li><b>Erythropoietin Regulation by Angiotensin II<br></b><i>Yong-Chul Kim, Ognoon Mungunsukh and Regina M. Day</i></li><li><b>Erythropoietin Receptor Signaling and Lipid Rafts<br></b><i>Kathy McGraw and Alan List</i></li><li><b>Erythropoietin and Hypothalamic-Pituitary Axis<br></b><i>Soumyadeep Dey and Constance T. Noguchi</i></li><li><b>Erythropoietin-Mediated Regulation of Central Respiratory Command<br></b><i>Tommy Seaborn and C�eline Caravagna</i></li><li><b>Mutual Cross Talk Between Iron Homeostasis and Erythropoiesis<br></b><i>Ilona Rybinska and Gaetano Cairo</i></li><li><b>Context-Dependent Skeletal Effects of Erythropoietin<br></b><i>Sahar Hiram-Bab, Drorit Neumann and Yankel Gabet</i></li><li><b>Erythropoietin-Mediated Neuroprotection in Insects Suggests a Prevertebrate Evolution of Erythropoietin-Like Signaling</b><br><i>Ralf Heinrich, Verena G�unther and Natasa Miljus</i></li><li><b>Erythropoietin: Endogenous Protection of Ischemic Brain<br></b><i>Robert T. Mallet and Myoung-Gwi Ryou</i></li><li><b>The Erythropoietin System Protects the Heart Upon Injury by Cardiac Progenitor Cell Activation<br></b><i>Maria P. Zafeiriou</i></li><li><b>Erythropoietin Promotes Glioblastoma via miR-451 Suppression<br></b><i>Begum Alural, Zeynep O. Ayyildiz, Kemal U. Tufekci, Sermin Genc and Kursad Genc</i></li><li><b>Erythropoietin, Stem Cell Factor, and Cancer Cell Migration<br></b><i>Maria J. Vazquez-Mellado, Victor M. Embriz and Leticia Rocha-Zavaleta</i></li><li><b>Significance of Erythropoietin Receptor Antagonist EMP9 in Cancers<br></b><i>Yoshiko Yasuda and Mitsugu Fujita</i><br></li></ol> |
| Descripción Física: | 1 online resource : illustrations |
| Bibliografía: | Includes bibliographical references. |
| ISBN: | 9780128122662 0128122668 012812265X 9780128122655 |