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A pharmacology primer : techniques for more effective and strategic drug discovery /
A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensa...
| Clasificación: | Libro Electrónico |
|---|---|
| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom ; San Diego, CA :
Academic Press, an imprint of Elsevier,
[2019]
|
| Edición: | Fifth edition. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 100 | 1 | |a Kenakin, Terrence P., |e author. | |
| 245 | 1 | 2 | |a A pharmacology primer : |b techniques for more effective and strategic drug discovery / |c Terry P. Kenakin, PhD, Professor, Department of Pharmacology, University of North Carolina School of Medicine, United States. |
| 250 | |a Fifth edition. | ||
| 264 | 1 | |a London, United Kingdom ; |a San Diego, CA : |b Academic Press, an imprint of Elsevier, |c [2019] | |
| 264 | 4 | |c �2019 | |
| 300 | |a 1 online resource : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric modulation -- The optimal design of pharmacological experiments -- Pharmacokinetics -- Safety pharmacology -- The drug discovery process -- Statistics and experimental design -- Selected pharmacological methods -- Exercises in pharmacodynamics and pharmacokinetics. | |
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed November 5, 2018). | |
| 520 | |a A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. | ||
| 650 | 0 | |a Pharmacology, Experimental. | |
| 650 | 0 | |a Drugs |x Dose-response relationship. | |
| 650 | 1 | 2 | |a Receptors, Drug |x physiology |0 (DNLM)D011955Q000502 |
| 650 | 2 | 2 | |a Dose-Response Relationship, Drug |0 (DNLM)D004305 |
| 650 | 2 | 2 | |a Pharmacology |x methods |0 (DNLM)D010600Q000379 |
| 650 | 6 | |a Pharmacologie exp�erimentale. |0 (CaQQLa)201-0089582 | |
| 650 | 6 | |a M�edicaments |x Relations dose-effet. |0 (CaQQLa)201-0023148 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Dose-response relationship |2 fast |0 (OCoLC)fst00898805 | |
| 650 | 7 | |a Pharmacology, Experimental |2 fast |0 (OCoLC)fst01060280 | |
| 776 | 0 | 8 | |i Print version: |a Kenakin, Terrence P. |t Pharmacology primer. |b Fifth edition. |d London, United Kingdom ; San Diego, CA : Academic Press, an imprint of Elsevier, [2019] |z 0128139579 |z 9780128139578 |w (OCoLC)1037806446 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128139578 |z Texto completo |