Protein prenylation. Part A /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Tamanoi, Fuyuhiko (Editor ), Hrycyna, Christine A. (Editor ), Bergo, Martin O. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, 2011.
Edición:1st ed.
Colección:Enzymes ; v. 29.
Temas:
Molecular biology.
Proteins.
Molecular Biology
Biologie mol�eculaire.
Prot�eines.
molecular biology.
protein.
SCIENCE > Life Sciences > Biochemistry.
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • 1. Protein Prenylation: A Perspective on Initial Discoveries / John A. Glomset
  • I. Abstract
  • II. Steps in the Trail of Research
  • References
  • 2. Insights into the Function of Prenylation from Nuclear Lamin Farnesylation / Michael Sinensky
  • I. Abstract
  • II. Introduction
  • III. Subcellullar Trafficking and Processing of Prelamin A
  • IV. Step 2 Endoprotease Activity and Zmpste24
  • V. Functional Aspects of Lamin Farnesylation
  • VI. Relationship of Lamin Prenylation to the Functional Role of Prenylation in Other Proteins
  • References
  • 3. Posttranslational Processing of Nuclear Lamins / Stephen G. Young
  • I. Abstract
  • II. Introduction
  • III. B-Type Lamins
  • IV. A-Type Lamins
  • V. Defects in Prelamin A Processing and Disease
  • VI. Alternate Prenylation of Prelamin A
  • VII. The Purpose of Prelamin A Processing
  • VIII. Concluding Thoughts
  • Acknowledgments
  • References
  • 4. Prenylated Proteins in Peroxisome Biogenesis / Ralf Erdmann
  • I. Abstract
  • II. Peroxisomes
  • III. Biogenesis of Peroxisomes
  • References
  • 5. Lipid Modification of Ras Superfamily GTPases: Not Just Membrane Glue / Channing J. Der
  • I. Abstract
  • II. Introduction
  • III. Ras Superfamily PrenyItransferases
  • IV. Ras Family Members
  • V. Rho Family Members
  • VI. Rab Family Members
  • VII. The Arf Family of Small GTPases
  • VIII. The Ran Small GTPase
  • IX. Prenyltransferases as Therapeutic Targets
  • X. Conclusion
  • Acknowledgments
  • References
  • 6. Heterogeneous Prenyl Processing of the Heterotrimeric G protein Gamma Subunits / John D. Hildebrandt
  • I. Abstract
  • II. Heterotrimeric G Proteins and Prenylation of the Gy Subunit
  • III. Functional Role of G Protein y Subunit Prenylation
  • IV. Variation in Prenyl Processing of Brain G Proteins
  • V. Conclusion
  • References
  • 7. Farnesylation Versus Geranylgeranylation in G-Protein-Mediated Light Signaling / Yoshitaka Fukada
  • I. Abstract
  • II. Introduction
  • III. Characteristic Properties of Phototransduction.

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