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|a OPELS
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|a 019066056
|2 Uk
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|a 1054376615
|a 1055044217
|a 1235842494
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|a 9780128134726
|q (electronic bk.)
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|a 0128134720
|q (electronic bk.)
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|z 9780128134719
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|z 0128134712
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|a (OCoLC)1054255128
|z (OCoLC)1054376615
|z (OCoLC)1055044217
|z (OCoLC)1235842494
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|a RC731
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|a 616.2
|2 23
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| 245 |
0 |
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|a Implementing precision medicine in best practices of chronic airway diseases /
|c edited by Ioana Agache, Peter Hellings.
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| 264 |
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1 |
|a London, United Kingdom :
|b Academic Press, an imprint of Elsevier,
|c [2019]
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| 264 |
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4 |
|c �2019
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| 300 |
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|a 1 online resource :
|b illustrations, map
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| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references and index.
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| 588 |
0 |
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|a Online resource; title from PDF title page (ScienceDirect, viewed September 26, 2018).
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| 505 |
0 |
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|a Front Cover; Implementing Precision Medicine in Best Practices of Chronic Airway Diseases; Copyright Page; Contents; List of Contributors; Foreword; I. The Concept of Precision Medicine and Precision Health; 1 The Audacious Goal of Precision Medicine; Further Reading; 2 Critical Entry Points-Genetics and Epigenetics; Critical Entry Points-Genetics and Epigenetics; Genetics: An Overview; Genetics of CRS; Epigenetics in CRS; Clinical Uses of Genetics and Genotyping in CRS; Characterization of Unexplained Immune Deficiencies; Assessment and Selection of Therapy for Cystic Fibrosis.
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| 505 |
8 |
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|a Predictive GeneticsTaste Receptors; Staphyloccus aureus Carriage in CRSwNP; Summary and Future Perspectives; 3 Critical Entry Points-Microbiome; Introduction; Microbiome Evolution in Early Life; Microbiome-Host Mechanisms; Microbiome in Asthma Patients; Microbiome in Allergic Rhinitis and Chronic Rhinosinusitis; Microbiome in Precision Medicine; Conclusions; References; 4 Factors Modulating the Disease Endotype; The complex immune-inflammatory network driving the endotype; The relation with the remodeled phenotype; The epigenetic influences; The role of the exposome.
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| 505 |
8 |
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|a Metabolic and endocrine pathwaysNeuroimmune factors; Conclusion; References; 5 Revised Disease Nomenclature Including Disease Endotypes; Introduction; Endotypes of Allergic Diseases; New Approach to Nomenclature; Asthma Endotypes; References; II. Shortcomings of Current Care Pathways for Chronic Airways Diseases; 6 The Global Burden of Chronic Airway Diseases; Introduction; References; 7 Unmet Needs in Chronic Upper Respiratory Tract Diseases; General Principles; Defining Patient Subpopulations; Etiology and Pathophysiology; Guidelines and Consensus Documents; Treatment; Conclusion.
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| 505 |
8 |
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|a Key PointsReferences; III. Personalized care: endotype-driven treatment; 8 Endotype-Driven Approach for Asthma; Asthma Phenotypes and Endotypes; Type-2 Asthma Endotype; Non-Type-2 Asthma Endotype; Conclusions; References; 9 Endotype-Driven Approach for Chronic Rhinosinusitis; Abbreviations; Introduction; Endotypes Based on T-Helper Cells; Endotyping of CRS; Treatment Approaches to Endotypes; Conclusion; Source of Funding; References; 10 Endotype-Driven Approach in Rhinitis; References; 11 Prevention of Allergies; Abbreviations; Introduction and Epidemiology; Primary Prevention.
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| 505 |
8 |
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|a Secondary PreventionTertiary Prevention; Risk Factors and Protective Factors; Genetic and Epigenetic Aspects; Family History and Allergy Susceptibility Genes; Epigenetic Regulation in Allergic Disease; Environmental Aspects; Siblings and Day Nursery; Farm Effect; Nutrition and Breastfeeding; Cesarean Section; Indoor Air; Pets; Outdoor Air Pollution; Climate Change; Occupational Allergies; Consequences for Allergy Prevention; Do's and Don'ts of Allergy Prevention; Research Needs and Outlook; Individualized Prevention; References; 12 Prevention of Asthma.
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| 650 |
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0 |
|a Respiratory organs
|x Diseases.
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| 650 |
|
2 |
|a Respiratory Tract Diseases
|0 (DNLM)D012140
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| 650 |
|
6 |
|a Appareil respiratoire
|x Maladies.
|0 (CaQQLa)201-0051369
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| 650 |
|
7 |
|a MEDICAL
|x Pulmonary & Thoracic Medicine.
|2 bisacsh
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| 650 |
|
7 |
|a Respiratory organs
|x Diseases
|2 fast
|0 (OCoLC)fst01095766
|
| 700 |
1 |
|
|a Agache, Ioana,
|e editor.
|
| 700 |
1 |
|
|a Hellings, Peter W.,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|a Agache, Ioana.
|t Implementing Precision Medicine in Best Practices of Chronic Airway Diseases.
|d San Diego : Elsevier Science & Technology, �2018
|z 9780128134719
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128134719
|z Texto completo
|
