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Medicinal chemistry : fundamentals /
Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific conc...
| Clasificación: | Libro Electrónico |
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| Autor principal: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, UK : Oxford, UK :
ISTE Press Ltd ; Elsevier Ltd,
2018.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Medicines and drugs
- Importance and evaluation of the pKa
- Importance and evaluation of lipophilicity
- Importance and evaluation of solubility
- Importance and evaluation of the polar surface area (PSA and TPSA)
- Lipinski's rule of five
- Principle of a prodrug
- Pharmacophore
- The European pharmacopoeia.