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Medicinal chemistry : fundamentals /

Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific conc...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Barret, Roland (Autor)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, UK : Oxford, UK : ISTE Press Ltd ; Elsevier Ltd, 2018.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Barret, Roland,  |e author. 
245 1 0 |a Medicinal chemistry :  |b fundamentals /  |c Roland Barret. 
264 1 |a London, UK :  |b ISTE Press Ltd ;  |a Oxford, UK :  |b Elsevier Ltd,  |c 2018. 
300 |a 1 online resource 
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504 |a Includes bibliographical references and index. 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed July 16, 2018). 
520 |a Medicinal Chemistry: Fundaments presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific concerns of the European Pharmacopeia - the industrialist's bible - its role, and a description of the monographs of active principles. 
505 0 |a Medicines and drugs -- Importance and evaluation of the pKa -- Importance and evaluation of lipophilicity -- Importance and evaluation of solubility -- Importance and evaluation of the polar surface area (PSA and TPSA) -- Lipinski's rule of five -- Principle of a prodrug -- Pharmacophore -- The European pharmacopoeia. 
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650 0 |a Pharmacopoeias. 
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