Cargando…
Antimicrobial peptides in gastrointestinal diseases /
Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMP...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London, United Kingdom :
Academic Press, an imprint of Elsevier,
2018.
|
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Antimicrobial Peptides in Gastrointestinal Diseases; Copyright; Contents; Contributors; General Introduction of Antimicrobial Peptides and Gastrointestinal Diseases; Chapter 1: Regulation of Cationic Antimicrobial Peptides Expression in the Digestive Tract; 1. Digestive Tract Microbiome as a Factor Regulating Expression of Cationic Antibacterial Peptides; 2. Factors Regulating Expression of AMPs and Molecular Mechanisms Governing This Process; 3. Regulation of AMPs Expression in Autoimmune Disorders Associated With the Gastrointestinal Tract
- 4. Stimulated Expression of AMPs in the Digestive Tract as a Potential New Method for Infection Treatment: A Great Altern ... 5. Conclusions; References; Chapter 2: Antimicrobial Peptides in the Host-Microbiota Homeostasis; 1. Background; 2. Characteristic of Microbiota; 2.1. Composition in the Skin Microbiome; 2.2. Composition in the Respiratory Tract Microbiome; 2.3. Composition in the Gastrointestinal Tract Microbiome; 3. Biological Function of Antimicrobial Peptides; 4. Antimicrobial Peptide as a Targeted Modulator on Human Microbiome; 5. Challenges and Future Avenues; References
- Further ReadingChapter 3: The Roles of Antimicrobial Peptides in the Regulation of Gastrointestinal Microbiota and Innate Immunity; 1. A Brief Introduction to Gastrointestinal Antimicrobial Peptides; 2. The Utility of AMPs as IBD Biomarkers; 3. Bacterial-Derived Substances Activate Innate Mucosal Immunity Via Cathelicidin Expression; 4. The Roles of AMPs in Gastrointestinal Infection and Inflammation; 5. The Roles of AMPs in Obesity, Liver Steatosis, and Metabolic Syndromes; 6. Concluding Remarks; References; Chapter 4: Cathelicidin in Gastrointestinal Disorders; 1. Introduction
- 2. The Distribution and Functions of Cathelicidin in the GI Tract2.1. The Distribution of Cathelicidin in the GI Tract; 2.2. The Functions of Cathelicidin in the GI Tract; 2.2.1. Mechanism of Antimicrobial Action; 2.2.2. Preventing Lipopolysaccharide (Lps)-Induced Inflammation; 2.2.3. Modulatory Influences in Inflammation; 2.2.4. Clearance of Active Inflammatory Mediators; 2.3. Cathelicidin and Wound Healing; 2.3.1. Angiogenic Influences; 2.3.2. Mitogenic and Promigratory Influences; 3. The Role of Cathelicidin in H. pylori Infection, Gastric Cancer, and Mucosal Repair in the Stomach
- 3.1. Cathelicidin and H. pylori Infection3.2. Cathelicidin and Gastric Cancer; 3.3. Cathelicidin and Wound Repair in the Stomach; 4. The Role of Cathelicidin in Ulcerative Colitis and Colon Cancer; 4.1. General Introduction to Ulcerative Colitis; 4.2. Intestinal Microbiota and Ulcerative Colitis; 4.3. Cathelicidin and Ulcerative Colitis; 4.4. Cathelicidin and Colon Cancer; 5. Final Conclusion Using Cathelicidin as a Potential Therapeutic Agent for GI Disorders; References; Chapter 5: Antimicrobial Peptides as Potential Therapy for Gastrointestinal Cancers: Opportunities and Challenges