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Palladium-catalyzed modification of nucleosides, nucleotides and oligonucleotides /
Annotation
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam, Netherlands :
Elsevier,
[2018]
|
| Colección: | Latest trends in palladium chemistry.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Palladium-catalyzed modification of nucleosides, nucleotides and oligonucleotides / |c edited by Anant R. Kapdi, Debabrata Maiti, Yogesh S. Sanghvi. |
| 264 | 1 | |a Amsterdam, Netherlands : |b Elsevier, |c [2018] | |
| 300 | |a 1 online resource : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Latest trends in palladium chemistry | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed June 11, 2018). | |
| 505 | 0 | |a Front Cover; Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides; Copyright; Contents; Contributors; Chapter 1: The Future of Drug Discovery: The Importance of Modified Nucleosides, Nucleotides, and Oligonucleotides; 1. Introduction; 2. Biologically Active Modified Nucleosides; 3. Synthetic Fluorescent Nucleoside Analogs; 4. Oligonucleotide Applications; 5. An Overview of Other Cross-Coupling Reactions in This Book; 6. Stille Cross-Coupling; 7. Suzuki-Miyaura Cross-Coupling; 8. Sonogashira reactions; 9. Heck Cross-Coupling. | |
| 505 | 8 | |a 10. Buchwald-Hartwig reactions11. C-H Activation Reactions; 12. Cross-Coupling of Nucleotides and Oligonucleotides; 13. Summary and Future Directions; References; Chapter 2: Stille Cross-Coupling Reaction: Early Years to the Current State of the Art; 1 Introduction; 2. Stille Coupling Reactions; 2.1 Early Developments; 3 Conclusion; References; Chapter 3: Suzuki-Miyaura Cross-Coupling as a Synthetic Tool for Nucleoside and Nucleotide Modification; 1. Introduction; 2. Suzuki-Miyaura Reaction: Mechanism and Conditions; 2.1 Overview of the Reaction. | |
| 505 | 8 | |a 2.2 Suzuki-Miyaura Reaction in Various Water-Based Catalytic Systems2.2.1 In Tetrahydrofuran/Methanol/Water; 2.2.2 In Dimethylether/Water; 2.2.3 In DMF/H2O; 2.2.4 In ACN/H2O; 2.2.5 In MeOH/H2O; 2.2.6 In H2O; 3. Palladium-Catalyzed Suzuki-Miyaura Routes to Modified Nucleosides; 3.1 Purine Nucleoside Analogues; 3.1.1 Modified Nucleosides at Purine Moiety; 3.1.2 Modified Flexible Nucleosides; 3.1.3 Carbocyclic Nucleosides Analogues; 3.2 Pyrimidine-Modified Analogues; 3.2.1 Arylation at C5- and C6- of Uridine/Cytidine Moiety. | |
| 505 | 8 | |a 3.2.2 Arylation of C5-Halo Uridine/Cytidine and C7-Halo Purine Nucleotides3.3 Miscellaneous; 4. Concluding Remarks; Acknowledgments; References; Chapter 4: Sonogashira Cross-Coupling: Alkyne-Modified Nucleosides and Their Applications; 1. Introduction; 2. General Reaction and the Mechanism of Classical Sonogashira Reaction; 3. Modifications of Sonogashira Coupling; 3.1 Modifications of Ligated Pd-Catalysts; 3.2 Generation of Ligand-Free Palladium Catalysts; 3.3 Palladium Nanoparticles as Catalysts. | |
| 505 | 8 | |a 3.4 Modified Form of Cu(I)-Co-Catalyst: Click Reagent Version of Sonogashira Coupling: Contribution From Our Group3.5 Cu-Free Sonogashira Coupling; 3.6 Ligand, Copper, and Amine-Free Palladium Catalyzed Sonogashira Coupling; 4. Applications of the Sonogashira Reaction; 5. Sonogashira Reaction in the Synthesis of Nucleoside; 6. Application of Sonogashira Coupling to Pyrimidine Nucleosides; 6.1 Synthesis of C-4-Substituted Pyrimidines; 6.2 Synthesis of C-5-Substituted Pyrimidines; 7. Sonogashira Coupling for the Synthesis of Substituted Purine Nucleosides. | |
| 520 | 8 | |a Annotation |b This volume describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. | |
| 650 | 0 | |a Palladium catalysts. | |
| 650 | 0 | |a Nucleosides. | |
| 650 | 0 | |a Nucleotides. | |
| 650 | 0 | |a Oligonucleotides. | |
| 650 | 2 | |a Nucleosides |0 (DNLM)D009705 | |
| 650 | 2 | |a Nucleotides |0 (DNLM)D009711 | |
| 650 | 2 | |a Oligonucleotides |0 (DNLM)D009841 | |
| 650 | 6 | |a Catalyseurs au palladium. |0 (CaQQLa)201-0109202 | |
| 650 | 6 | |a Nucl�eosides. |0 (CaQQLa)201-0085185 | |
| 650 | 6 | |a Nucl�eotides. |0 (CaQQLa)201-0012930 | |
| 650 | 6 | |a Oligonucl�eotides. |0 (CaQQLa)201-0162366 | |
| 650 | 7 | |a SCIENCE |x Chemistry |x Physical & Theoretical. |2 bisacsh | |
| 650 | 7 | |a Nucleosides |2 fast |0 (OCoLC)fst01041098 | |
| 650 | 7 | |a Nucleotides |2 fast |0 (OCoLC)fst01041118 | |
| 650 | 7 | |a Oligonucleotides |2 fast |0 (OCoLC)fst01045453 | |
| 650 | 7 | |a Palladium catalysts |2 fast |0 (OCoLC)fst01051700 | |
| 700 | 1 | |a Kapdi, Anant R., |e editor. | |
| 700 | 1 | |a Maiti, Debabrata, |e editor. | |
| 700 | 1 | |a Sanghvi, Yogesh S., |d 1956- |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Palladium-catalyzed modification of nucleosides, nucleotides and oligonucleotides. |d Amsterdam, Netherlands : Elsevier, [2018] |z 9780128112922 |z 0128112921 |w (OCoLC)1002834729 |
| 830 | 0 | |a Latest trends in palladium chemistry. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780128112922 |z Texto completo |