Inflammation and immunity in depression : basic science and clinical applications /

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"Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recen...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Baune, Bernhard T. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London, United Kingdom : Academic Press, an imprint of Elsevier, 2018.
Temas:
Depression, Mental > Immunological aspects.
Inflammation.
Depression > etiology
Depression > immunology
Depressive Disorder > etiology
Inflammation > etiology
Inflammation > psychology
Inflammation
D�epression > Immunologie.
Inflammation (Pathologie)
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Internet Resources.
Charts.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Inflammation and Immunity in Depression: Basic Science and Clinical Applications; Copyright; Contents; Contributors; Preface; Chapter 1: Depression-Associated Cellular Components of the Innate and Adaptive Immune System; The Innate Immune System; Role of Neutrophils in Innate Immunity and MDD; Monocytes and MDD; Innate Lymphoid Cells (ILCs) and Natural Killer (NK) Cells; NK Cells and Depression; The Adaptive Immune System and Its Components; Summary; References
  • Chapter 2: Childhood Microbial Experience, Immunoregulation, Inflammation, and Adult Susceptibility to Psychosocial Stres ... Introduction; Microbial Exposures and Human Evolution; Microbiota; Spores; Environmental Microorganisms; Old Infections; Innate and Adaptive Immune Systems Regulate Microbiota; Innate Immune System and Microbiota; Adaptive Immune System and Microbiota; Mechanisms of Immunoregulation by the Old Friends; Immunoregulation by the Old Infections; Immunoregulation by Organisms From the Natural Environment; Immunoregulation by the Microbiota; Endotoxin Tolerance
  • Microbial ExosomesLifestyle Changes That Impair Microbe-Induced Immunoregulation and That May Be Associated With Depression; Perinatal and Early-Life Antibiotic Exposure; Animal Experiments; Human Data; Caesarean Delivery; Breast Feeding; Diet; Maternal Obesity; Immigration; Stress; Depression; Chronic Stress-Induced Inflammation in Depression; Proinflammatory Cytokines Induce Depression; Depression is Associated With Autoimmune, Allergic and Inflammatory Bowel Disorders; Antidepressant Effects of Anti-Inflammatory and Immunoregulatory Treatments; Microbiota in Human Depression; Animal Data
  • Microbial Metabolites and the BrainConclusions; References; Chapter 3: Neuroendocrine Abnormalities in Major Depression: An Insight Into Glucocorticoids, Cytokines, and the Kynureni ... ; Introduction; The HPA Axis and Glucocorticoid Abnormalities in Major Depression; Glucocorticoid Resistance; Inflammation and Cytokine Dysregulation in Major Depression; Neuroinflammation; Serotonin-Kynurenine Hypothesis and Neurodegeneration; Summary and Conclusion; Future Directions and Translational Significance; References
  • Chapter 4: Neurovascular Dysfunction With BBB Hyperpermeability Related to the Pathophysiology of Major Depressive DisorderIntroduction; Neurovascular Dysfunction; Blood-Brain Barrier Unit Hyperpermeability; Theoretical Integration With Oxidative and Neuroinflammatory Mechanisms; Oxidative Stress; Neuroinflammation; Conclusions; References; Further Reading; Chapter 5: The Impact of Inflammation on Brain Function and Behavior in Rodent Models of Affective Disorders; Introduction; Stress, Inflammation and Depressive-Like Behaviors in Rodent Models

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