Stem Cells and Cancer in Hepatology : From the Essentials to Application /

Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Zheng, Yun-Wen (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Academic Press, An imprint of Elsevier, [2018]
Temas:
Hepatology.
Stem cells.
Liver > Diseases.
Liver > Cancer.
Liver > cytology
Stem Cells > physiology
Stem Cells > pathology
Liver Neoplasms > physiopathology
Cell Transplantation
Gastroenterology
Stem Cells
Liver Neoplasms
H�epatologie.
Cellules souches.
Foie > Cancer.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Hepatology
Liver > Cancer
Liver > Diseases
Stem cells
Internet Resources.
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Title Page; Copyright Page; Dedication; Contents; List of Contributors; Editor Biography; Foreword; Liver stem cells: are they real or illusions?; Preface; Acknowledgments; Introduction; References; Chapter 1
  • Molecular Mechanisms of Liver Development: Lessons From Animal Models; 1
  • Introduction; 2
  • Liver development; 2.1
  • Chronology of Liver Bud Formation; 2.2
  • Genes Involved in Liver Bud Formation; 2.3
  • Hepatocyte and Cholangiocyte Differentiation; 2.4
  • Mesothelial Cell Differentiation; 2.5
  • Hepatic Stellate Cell Differentiation; 2.6
  • LSEC Differentiation
  • 2.7
  • Differentiation of Kupffer Cells and Pit Cells3
  • Studies of liver formation using zebrafish; 4
  • Studies of liver formation using medaka; 4.1
  • Group 1: Mutations Affecting Hepatoblast Development; 4.2
  • Group 2: Mutations Affecting Hepatoblast Proliferation; 4.3
  • Group 3: Mutations Affecting Liver Laterality; 4.4
  • Group 4: Mutations Affecting Hemoglobin-Bilirubin Metabolism; 4.5
  • Group 5: Mutations Affecting Lipid Metabolism; 4.6
  • Analysis of Medaka Mutants; 5
  • Studies of liver size regulation in mice; 6
  • Human liver diseases; 6.1
  • Hepatocellular Carcinoma
  • 6.2
  • Metabolic Disorders6.3
  • Alagille Syndrome; 7
  • Conclusion; List of acronyms and abbreviations; References; Chapter 2
  • Molecular Mechanisms Regulating the Proliferation and Maturation of Hepatic Progenitor Cells During Liver Devel ... ; 1
  • Introduction; 2
  • Liver regeneration and normal liver-derived stem/progenitor cells; 3
  • Regulation of transcription factors regulating the proliferation and maturation of hepatic progenitor cells; 4
  • Signaling pathways regulating hepatoblast proliferation and differentiation; 5
  • Hepatic progenitor cells derived from human pluripotent stem cells
  • 6
  • ConclusionFinancial support and sponsorship; Acknowledgments; List of abbreviations; References; Chapter 3
  • Plasticity of Liver Epithelial Cells in Healthy and Injured Livers; 1
  • Introduction; 2
  • Lineage specification during development; 3
  • Lineage plasticity and heterogeneity of cholangiocytes; 3.1
  • Lineage Plasticity of Cholangiocytes; 3.1.1
  • Fetal and Neonatal Cholangiocytes; 3.1.2
  • Adult Cholangiocytes; 3.2
  • Heterogeneity of Cholangiocytes; 3.3
  • Molecular Mechanisms Regulating the Plasticity of Cholangiocytes; 4
  • Lineage plasticity and heterogeneity of hepatocytes
  • 5.2
  • Histone Modification and Chromatin Structure

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