|
|
|
|
| LEADER |
00000cam a2200000 i 4500 |
| 001 |
SCIDIR_on1035556367 |
| 003 |
OCoLC |
| 005 |
20231120010254.0 |
| 006 |
m o d |
| 007 |
cr cnu---unuuu |
| 008 |
180514s2018 enk ob 001 0 eng d |
| 040 |
|
|
|a N$T
|b eng
|e rda
|e pn
|c N$T
|d OPELS
|d N$T
|d EBLCP
|d YDX
|d D6H
|d MERER
|d OCLCF
|d CASUM
|d SNM
|d OCLCQ
|d UAB
|d OCLCO
|d OCLCQ
|d OTZ
|d AU@
|d OCLCO
|d UKMGB
|d OCLCO
|d U3W
|d OCLCO
|d OCLCA
|d OCLCQ
|d LVT
|d OCLCA
|d OCLCQ
|d OCLCO
|d OCLCQ
|d OCLCA
|d S2H
|d OCLCO
|d OCLCA
|d OCLCQ
|d OCLCO
|d K6U
|d OCLCQ
|d OCLCO
|
| 015 |
|
|
|a GBB897225
|2 bnb
|
| 016 |
7 |
|
|a 018881717
|2 Uk
|
| 019 |
|
|
|a 1036772942
|a 1041916675
|a 1050722868
|a 1229748870
|
| 020 |
|
|
|a 9780128128046
|q (electronic bk.)
|
| 020 |
|
|
|a 0128128046
|q (electronic bk.)
|
| 020 |
|
|
|z 9780128127742
|q (print)
|
| 020 |
|
|
|z 0128127740
|
| 035 |
|
|
|a (OCoLC)1035556367
|z (OCoLC)1036772942
|z (OCoLC)1041916675
|z (OCoLC)1050722868
|z (OCoLC)1229748870
|
| 050 |
|
4 |
|a RC269.7
|b .D5 2018eb
|
| 060 |
|
4 |
|a QZ 241
|
| 072 |
|
7 |
|a HEA
|x 039000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 014000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 022000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 112000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 045000
|2 bisacsh
|
| 082 |
0 |
4 |
|a 616.99/4
|2 23
|
| 245 |
0 |
0 |
|a Diagnostic and therapeutic applications of exosomes in cancer /
|c edited by Mansoor Amiji, Rajagopal Ramesh.
|
| 264 |
|
1 |
|a London, United Kingdom :
|b Academic Press,
|c 2018.
|
| 300 |
|
|
|a 1 online resource
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Includes index.
|
| 588 |
0 |
|
|a Online resource; title from PDF title page (ScienceDirect, viewed May 16, 2018).
|
| 505 |
0 |
|
|a Intro; Title page; Table of Contents; Copyright; Dedication; List of Contributors; Preface; Acknowledgments; 1. Introduction to Exosomes and Cancer; 1. A Brief History; 2. Biogenesis; 3. Isolation and Characterization; 4. Content; 5. Biological Function in Cancer; 2. Extracellular Vesicle Biogenesis in Cancer; 1. Introduction; 2. Microvesicle Biogenesis; 3. Exosome Biogenesis; 4. An Increasing Importance of Examining Diverse Vesicles; 5. CD63-Dependent Vesicle Production; 6. Vesicle Secretion Is Linked to Intercellular Signaling
|
| 505 |
8 |
|
|a 3. Composition, Physicochemical and Biological Properties of Exosomes Secreted From Cancer Cells1. Introduction; 2. Exosome Biogenesis; 3. Factors Affecting the Release of Exosomes From Cancer Cells; 4. Composition of Exosomes; 5. Size and Charge of Cancer Exosomes; 6. Summary and Future Considerations; 4. Heterogeneity of Tumor Exosomes -- Role in Precision Medicine; 1. Introduction; 2. Double-Stranded Genomic DNA in Circulating Exosomes; 3. Detection of Mutational Signatures in Genomic DNA-Enriched Exosomes; 4. Exosomes as Agents for Early Detection, Diagnosis, and Stratification
|
| 505 |
8 |
|
|a 5. Genomic Molecular Profiling of Exosomal Cargo6. Transcriptomic Characterization of Tumors Through Liquid Biopsies; 7. Conclusions; 5. Proteomic Profiling of Tumor Exosomes; 1. Introduction; 2. Sources of Exosomes; 3. Proteomic Content of Exosomes in Cancers; 4. Conclusion; 6. Nucleic Acid Profiling in Tumor Exosomes; 1. Introduction; 2. Composition of Exosomes; 3. Nucleic Acid Loading Into Exosomes; 4. Isolation Techniques for RNA/DNA From Exosomes; 5. Profiling of Nucleic Acid-RNA; 6. Single EV Analysis; 7. Statistical and Bioinformatic Software for evRNA Characterization
|
| 505 |
8 |
|
|a 8. Experimental Artifacts and Contaminants Affecting evRNA Analysis9. Conclusions; 7. Nanotechnology Platforms for Cancer Exosome Analyses; 1. Introduction; 2. Nanoplasmonic Sensing; 3. Electrochemical Sensing; 4. Immunomagnetic Exosome RNA Analysis; 5. Conclusions; 8. Exosome RNAs as Biomarkers and Targets for Cancer Therapy; 1. Introduction; 2. History of RNA in Exosomes; 3. RNA Species Present in Exosomes; 4. Sources of Exosomes; 5. Technology for the Study of Exosomal miRNA; 6. Challenges and Perspective; 7. Conclusion; 9. Diagnostic Potential of Tumor Exosomes; 1. Introduction
|
| 505 |
8 |
|
|a 2. Methods and Tools for Exosome Isolation3. Tumor Exosomes for Cancer Diagnosis; 4. Additional Diagnostic Potential of Exosomes; 5. Conclusion/Discussion; 10. Biodistribution of Cancer-Derived Exosomes; 1. Introduction; 2. Mechanisms Involved in Tumor-Derived Exosomes Homing to Specific Organs; 3. Impact of Diverse Factors on the Evaluation of Exosome Biodistribution In Vivo; 4. Conclusions; 11. Exosome-Mediated Communication in the Tumor Microenvironment; 1. Introduction; 2. Exosomes and the Tumor Microenvironment; 3. Exosome-Mediated Cellular Reprogramming; 4. Future Prospects
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 650 |
|
0 |
|a Cancer
|x Molecular aspects.
|
| 650 |
|
0 |
|a Cancer
|x Molecular diagnosis.
|
| 650 |
1 |
2 |
|a Exosomes
|0 (DNLM)D055354
|
| 650 |
1 |
2 |
|a Neoplasms
|x microbiology
|0 (DNLM)D009369Q000382
|
| 650 |
1 |
2 |
|a Neoplasms
|x diagnosis
|0 (DNLM)D009369Q000175
|
| 650 |
|
6 |
|a Cancer
|x Aspect mol�eculaire.
|0 (CaQQLa)201-0212614
|
| 650 |
|
6 |
|a Cancer
|x Diagnostic mol�eculaire.
|0 (CaQQLa)201-0247470
|
| 650 |
|
6 |
|a Exosomes.
|0 (CaQQLa)000275754
|
| 650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Diseases.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a Cancer
|x Molecular aspects
|2 fast
|0 (OCoLC)fst00845397
|
| 650 |
|
7 |
|a Cancer
|x Molecular diagnosis
|2 fast
|0 (OCoLC)fst00845398
|
| 655 |
|
4 |
|a Internet Resources.
|
| 655 |
|
4 |
|a Charts.
|
| 700 |
1 |
|
|a Amiji, Mansoor M.,
|e editor.
|
| 700 |
1 |
|
|a Ramesh, Rajagopal,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Diagnostic and therapeutic applications of exosomes in cancer.
|d London, United Kingdom : Academic Press, 2018
|z 0128127740
|z 9780128127742
|w (OCoLC)1007045522
|
| 856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780128127742
|z Texto completo
|
